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引用本文的文献

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Electron spin resonance (ESR) spectrum of paraffin embedded human liver tissue. A possible method for the estimation of copper content.石蜡包埋的人体肝脏组织的电子自旋共振（ESR）光谱。一种估算铜含量的可能方法。
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2
ESR study of development of RFM/Un murine myeloid leukaemia.RFM/Un小鼠髓性白血病发育的电子自旋共振研究
Br J Cancer. 1978 Nov;38(5):612-8. doi: 10.1038/bjc.1978.257.
3
Electron spin resonance study of changes during development of solid yoshida tumour. II. Paramagnetic metal ions.吉田实体瘤发育过程中变化的电子自旋共振研究。II. 顺磁性金属离子。
Br J Cancer. 1976 Nov;34(5):556-65. doi: 10.1038/bjc.1976.211.
4
Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical.小鼠髓性白血病发育过程中变化的电子自旋共振研究。II. 抗坏血酸自由基。
Br J Cancer. 1975 Oct;32(4):451-5. doi: 10.1038/bjc.1975.246.

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AN ELECTRON SPIN RESONANCE STUDY OF NEOPLASMS.肿瘤的电子自旋共振研究
Cancer Res. 1963 Jul;23:833-40.
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THE SPECIFIC BINDING OF IRON(III) AND COPPER(II) TO TRANSFERRIN AND CONALBUMIN.铁（III）和铜（II）与转铁蛋白和伴清蛋白的特异性结合
Biochim Biophys Acta. 1963 Sep 24;75:203-22. doi: 10.1016/0006-3002(63)90599-7.
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The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum.正常人血清中铜蓝蛋白亚铁氧化酶活性的潜在意义。
J Biol Chem. 1966 Jun 25;241(12):2746-51.
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Prolonged observations on variations in the serum copper in Hodgkin's disease.
Clin Radiol. 1969 Jul;20(3):247-56. doi: 10.1016/s0009-9260(69)80138-8.
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Role of iron in the oxidase activity of ceruloplasmin.
Biochim Biophys Acta. 1968 Mar 25;151(3):541-57. doi: 10.1016/0005-2744(68)90001-6.
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Serum copper levels in lymphoma and leukemia. Special reference to Hodgkin's disease.淋巴瘤和白血病患者的血清铜水平。特别提及霍奇金病。
Cancer. 1968 Apr;21(4):743-55. doi: 10.1002/1097-0142(196804)21:4<743::aid-cncr2820210427>3.0.co;2-a.
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Serum copper observations in patients with malignant lymphoma.恶性淋巴瘤患者的血清铜观察
Cancer. 1973 Dec;32(6):1512-24. doi: 10.1002/1097-0142(197312)32:6<1512::aid-cncr2820320631>3.0.co;2-p.
8
Invited discussion: Value of fluctuations in the serum copper level in the control of patients with Hodgkin's disease.
Natl Cancer Inst Monogr. 1973 May;36:325-6.
9
Serum copper as an index of tumor response to radiotherapy.血清铜作为肿瘤放疗反应指标。
Radiology. 1973 Mar;106(3):635-9. doi: 10.1148/106.3.635.
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Significance of serum copper levels in adult patients with Hodgkin's disease.
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小鼠髓系白血病发展过程中变化的电子自旋共振研究。I. 顺磁性金属离子。

Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. I. Paramagnetic metal ions.

作者信息

Dodd N J

出版信息

Br J Cancer. 1975 Jul;32(1):108-20. doi: 10.1038/bjc.1975.137.

DOI:10.1038/bjc.1975.137
PMID:169866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2024794/
Abstract

The blood, spleen and liver of mice were examined by means of electron spin resonance (e.s.r.), throughout the course of myeloid leukaemia induced by intravenous injection of leukaemic spleen cells. In blood, marked increases in the concentrations of iron transferrin and ceruloplasmin occurred within the first 3 days after injection. In the spleen, changes in the concentrations of paramagnetic copper and iron complexes were detectable by about the 5th day, before any measurable splenic enlargement, whilst in the liver changes were detectable by about the 8th day. The changes occurring in blood, spleen and liver during the development of leukaemia appear to be related and they are discussed in terms of iron transport.

摘要

在通过静脉注射白血病脾细胞诱导小鼠发生髓性白血病的整个过程中，采用电子自旋共振（e.s.r.）技术对小鼠的血液、脾脏和肝脏进行了检查。在血液中，注射后第1个3天内转铁蛋白和铜蓝蛋白的浓度显著增加。在脾脏中，大约在第5天可检测到顺磁性铜和铁络合物浓度的变化，此时脾脏尚无任何可测量的肿大，而在肝脏中，大约在第8天可检测到变化。白血病发展过程中血液、脾脏和肝脏中发生的变化似乎是相关的，并且从铁转运的角度对这些变化进行了讨论。