Joshi P, Glick B
Poultry Science Department, Mississippi State University.
Dev Comp Immunol. 1990 Summer;14(3):319-25. doi: 10.1016/0145-305x(90)90022-7.
Lymphocyte inhibitory factor (LyIF) and lymphocyte chemotactic factor (LCF) were produced by sensitized thymic (T) and bursal (B) cells and thymic (T) cells, respectively. The passage of sensitized T and B cells through a Sephadex G-10 column abrogated the ability of T cells to produce LyIF and LCF while B cells remained capable of producing LyIF. The return of macrophages to the adherent cell depleted population reconstituted the T cells' ability to produce LyIF and LCF. These data suggest a greater macrophage dependency of thymic cells than bursal cells in the production of lymphokines.
淋巴细胞抑制因子（LyIF）和淋巴细胞趋化因子（LCF）分别由致敏胸腺（T）细胞和法氏囊（B）细胞以及胸腺（T）细胞产生。致敏T细胞和B细胞通过葡聚糖G - 10柱后，T细胞产生LyIF和LCF的能力丧失，而B细胞仍能产生LyIF。巨噬细胞回到去除贴壁细胞的群体中后，T细胞产生LyIF和LCF的能力得以恢复。这些数据表明，在淋巴因子的产生过程中，胸腺细胞比法氏囊细胞对巨噬细胞的依赖性更强。
