ptsN基因产物在恒化器培养中恶臭假单胞菌TOL甲苯降解途径的分解代谢物阻遏中的作用。
Role of the ptsN gene product in catabolite repression of the Pseudomonas putida TOL toluene degradation pathway in chemostat cultures.
作者信息
Aranda-Olmedo Isabel, Marín Patricia, Ramos Juan L, Marqués Silvia
机构信息
Consejo Superior de Investigaciones Científicas, Estación Experimental del Zaidín, Dept. of Environmental Protection, Granada E-18008, Spain.
出版信息
Appl Environ Microbiol. 2006 Nov;72(11):7418-21. doi: 10.1128/AEM.01067-06. Epub 2006 Sep 22.
Abstract
The Pseudomonas putida KT2440 TOL upper pathway is repressed under nonlimiting conditions in cells growing in chemostat with succinate as a carbon source. We show that the ptsN gene product IIA(Ntr) participates in this repression. Crc, involved in yeast extract-dependent repression in batch cultures, did not influence expression when cells were growing in a chemostat with succinate at maximum rate.
摘要
恶臭假单胞菌KT2440的TOL上途径在以琥珀酸盐作为碳源的恒化器中生长的细胞处于非限制条件下时受到抑制。我们表明ptsN基因产物IIA(Ntr)参与了这种抑制作用。在分批培养中参与酵母提取物依赖性抑制的Crc，当细胞在以琥珀酸盐为碳源的恒化器中以最大速率生长时，对表达没有影响。
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本文引用的文献
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Levels and activity of the Pseudomonas putida global regulatory protein Crc vary according to growth conditions.恶臭假单胞菌全局调控蛋白Crc的水平和活性会根据生长条件而变化。
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Genetic evidence that catabolites of the Entner-Doudoroff pathway signal C source repression of the sigma54 Pu promoter of Pseudomonas putida.有遗传学证据表明，恶臭假单胞菌σ54 Pu启动子的碳源阻遏是由Entner-Doudoroff途径的分解代谢物发出信号的。
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The Pseudomonas putida Crc global regulator controls the expression of genes from several chromosomal catabolic pathways for aromatic compounds.恶臭假单胞菌Crc全局调控因子控制来自几个染色体芳香族化合物分解代谢途径的基因表达。
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