Ghosh Dhruva Nath, Sen Sudipta, Chacko Jacob, Thomas Gordon, Karl Sampath, Mathai John
Department of Paediatric Surgery, Christian Medical College and Hospital, Vellore, Tamil Nadu 632004, India.
Pediatr Surg Int. 2007 Jan;23(1):65-8. doi: 10.1007/s00383-006-1793-6. Epub 2006 Sep 26.
The leaking pancreatic duct in childhood chronic pancreatitis presents with ascites and pleural effusion and is a potentially lethal condition. Seven children with this condition were seen in the period 2003-2006. The correct diagnosis was not entertained till a raised serum amylase was discovered. The diagnosis was confirmed by very high levels of amylase in the aspirated abdominal or pleural fluid. Computerized tomogram was the most useful imaging study and demonstrated a dilated pancreatic duct. All children were operated within 6 days of diagnosis by a Puestow's procedure in six and peripancreatic drainage in one. Six children made a prompt and lasting recovery after a Puestow's procedure while one child, also suffering from metastatic neuroblastoma, died in the immediate post operative period after peripancreatic drainage. We recommend prompt and definitive surgical management of this potentially lethal condition.
儿童慢性胰腺炎中胰管渗漏表现为腹水和胸腔积液,是一种潜在的致命疾病。在2003年至2006年期间共诊治了7例患有这种疾病的儿童。直到发现血清淀粉酶升高才考虑到正确的诊断。通过抽吸的腹腔或胸腔积液中淀粉酶水平极高来确诊。计算机断层扫描是最有用的影像学检查,显示胰管扩张。所有儿童在诊断后6天内接受手术,6例行普斯托手术,1例行胰周引流术。6例儿童在接受普斯托手术后迅速并持久康复,而1例同时患有转移性神经母细胞瘤的儿童在胰周引流术后即刻死亡。我们建议对这种潜在的致命疾病进行迅速而明确的手术治疗。