Satoh Tatsunori, Kikuyama Masataka, Yokoi Yoshihiro, Kawaguchi Shinya
Department of Gastroenterology, Shizuoka General Hospital, 4-27-1, Kita-ando, Aoiku, Shizuoka, 420-8527, Japan.
Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan.
Clin J Gastroenterol. 2017 Apr;10(2):191-195. doi: 10.1007/s12328-017-0720-9. Epub 2017 Feb 24.
A 66-year-old man was admitted for severe acute alcoholic pancreatitis with infected pancreatic necrosis (IPN). Abdominal computed tomography revealed an inflamed pancreatic head, a dilated main pancreatic duct (MPD), and a large cavity with heterogeneous fluid containing gas adjacent to the pancreatic head, and extending to the pelvis. The cavity was drained percutaneously near the pancreatic head on admission; another tube was inserted into the pelvic cavity on hospital day 3. The drained fluid contained pus with high amylase concentration. Nasopancreatic drainage tube placement was unsuccessfully attempted on hospital day 9. On hospital day 23, percutaneous puncture of the MPD and placement of a pancreatic duct drainage tube was performed. Pancreatography revealed major extravasation from the pancreatic head. The IPN cavity receded; the percutaneous IPN drainage tube was removed on hospital day 58. On hospital day 83, the pancreatic drainage was changed to a transpapillary pancreatic stent, and the patient was discharged. Measuring the amylase concentration of peripancreatic fluid collections can aid in the diagnosis of pancreatic duct disruption; moreover, dual percutaneous necrotic cavity drainage plus pancreatic duct drainage may be essential for treating IPN. If transpapillary drainage tube placement is difficult, percutaneous pancreatic duct drainage may be feasible.
一名66岁男性因重症急性酒精性胰腺炎合并感染性胰腺坏死(IPN)入院。腹部计算机断层扫描显示胰头炎症、主胰管扩张,以及胰头附近有一个大腔,腔内有含气的不均质液体,并延伸至盆腔。入院时在胰头附近经皮穿刺引流该腔;住院第3天在盆腔置入另一根引流管。引流液含有高淀粉酶浓度的脓液。住院第9天尝试放置鼻胰引流管未成功。住院第23天,对主胰管进行经皮穿刺并放置胰管引流管。胰管造影显示胰头有大量造影剂外渗。IPN腔缩小;住院第58天拔除经皮IPN引流管。住院第83天,将胰管引流改为经乳头胰管支架置入,患者出院。检测胰周液体中的淀粉酶浓度有助于诊断胰管破裂;此外,经皮双腔坏死腔引流加胰管引流可能是治疗IPN的关键。如果经乳头放置引流管困难,经皮胰管引流可能可行。