• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

无家可归吸毒者对同伴“带回家的纳洛酮”使用的认知与风险感知——一项定性研究

Homeless drug users' awareness and risk perception of peer "take home naloxone" use--a qualitative study.

作者信息

Wright Nat, Oldham Nicola, Francis Katharine, Jones Lesley

机构信息

Healthcare Department, HMP Leeds, Leeds, UK.

出版信息

Subst Abuse Treat Prev Policy. 2006 Oct 2;1:28. doi: 10.1186/1747-597X-1-28.

DOI:10.1186/1747-597X-1-28
PMID:17014725
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1599711/
Abstract

BACKGROUND

Peer use of take home naloxone has the potential to reduce drug related deaths. There appears to be a paucity of research amongst homeless drug users on the topic. This study explores the acceptability and potential risk of peer use of naloxone amongst homeless drug users. From the findings the most feasible model for future treatment provision is suggested.

METHODS

In depth face-to-face interviews conducted in one primary care centre and two voluntary organisation centres providing services to homeless drug users in a large UK cosmopolitan city. Interviews recorded, transcribed and analysed thematically by framework techniques.

RESULTS

Homeless people recognise signs of a heroin overdose and many are prepared to take responsibility to give naloxone, providing prior training and support is provided. Previous reports of the theoretical potential for abuse and malicious use may have been overplayed.

CONCLUSION

There is insufficient evidence to recommend providing "over the counter" take home naloxone" to UK homeless injecting drug users. However a programme of peer use of take home naloxone amongst homeless drug users could be feasible providing prior training is provided. Peer education within a health promotion framework will optimise success as current professionally led health promotion initiatives are failing to have a positive impact amongst homeless drug users.

摘要

背景

同伴使用纳洛酮带回家有减少与药物相关死亡的潜力。在无家可归的吸毒者中,关于该主题的研究似乎很少。本研究探讨了无家可归吸毒者中同伴使用纳洛酮的可接受性和潜在风险。根据研究结果,提出了未来治疗提供的最可行模式。

方法

在英国一个大城市的一个初级保健中心和两个为无家可归吸毒者提供服务的志愿组织中心进行了深入的面对面访谈。访谈进行录音、转录,并采用框架技术进行主题分析。

结果

无家可归者能识别海洛因过量的迹象,并且如果提供了事先培训和支持,许多人愿意承担给予纳洛酮的责任。先前关于滥用和恶意使用的理论可能性的报道可能被夸大了。

结论

没有足够的证据推荐向英国无家可归的注射吸毒者提供“非处方”带回家的纳洛酮。然而,如果提供事先培训,在无家可归吸毒者中开展同伴使用带回家纳洛酮的项目可能是可行的。在健康促进框架内的同伴教育将优化成功几率,因为目前由专业人员主导的健康促进举措未能对无家可归吸毒者产生积极影响。

相似文献

1
Homeless drug users' awareness and risk perception of peer "take home naloxone" use--a qualitative study.无家可归吸毒者对同伴“带回家的纳洛酮”使用的认知与风险感知——一项定性研究
Subst Abuse Treat Prev Policy. 2006 Oct 2;1:28. doi: 10.1186/1747-597X-1-28.
2
Is a randomised controlled trial of take home naloxone distributed in emergency settings likely to be feasible and acceptable? Findings from a UK qualitative study exploring perspectives of people who use opioids and emergency services staff.在急诊环境中分发可携带纳洛酮的随机对照试验是否可行和可接受?一项英国定性研究探索了阿片类药物使用者和急诊服务人员的观点。
BMC Emerg Med. 2024 Apr 29;24(1):75. doi: 10.1186/s12873-024-00987-y.
3
Naloxone and the Inner City Youth Experience (NICYE): a community-based participatory research study examining young people's perceptions of the BC take home naloxone program.纳洛酮与内城青少年体验(NICYE):一项基于社区的参与性研究,考察年轻人对不列颠哥伦比亚省纳洛酮带回家计划的看法。
Harm Reduct J. 2017 Jun 7;14(1):34. doi: 10.1186/s12954-017-0160-3.
4
Physicians' knowledge of and willingness to prescribe naloxone to reverse accidental opiate overdose: challenges and opportunities.医生对开具纳洛酮以逆转意外阿片类药物过量的了解及意愿:挑战与机遇
J Urban Health. 2007 Jan;84(1):126-36. doi: 10.1007/s11524-006-9120-z.
5
Attitudes of Australian heroin users to peer distribution of naloxone for heroin overdose: perspectives on intranasal administration.澳大利亚海洛因使用者对同伴分发用于海洛因过量解毒的纳洛酮的态度:关于鼻内给药的观点。
J Urban Health. 2008 May;85(3):352-60. doi: 10.1007/s11524-008-9273-z. Epub 2008 Mar 18.
6
Naloxone distribution and cardiopulmonary resuscitation training for injection drug users to prevent heroin overdose death: a pilot intervention study.为预防海洛因过量致死向注射吸毒者分发纳洛酮及进行心肺复苏培训:一项试点干预研究
J Urban Health. 2005 Jun;82(2):303-11. doi: 10.1093/jurban/jti053. Epub 2005 May 4.
7
Cost-Effectiveness of Take-Home Naloxone for the Prevention of Overdose Fatalities among Heroin Users in the United Kingdom.在英国,将纳洛酮带回家用于预防海洛因使用者过量死亡的成本效益。
Value Health. 2018 Apr;21(4):407-415. doi: 10.1016/j.jval.2017.07.014. Epub 2018 Feb 4.
8
Attitudes about prescribing take-home naloxone to injection drug users for the management of heroin overdose: a survey of street-recruited injectors in the San Francisco Bay Area.关于为注射吸毒者开具可带回家的纳洛酮以应对海洛因过量的态度:对旧金山湾区街头招募的注射吸毒者的一项调查。
J Urban Health. 2003 Jun;80(2):291-301. doi: 10.1093/jurban/jtg032.
9
Take-home emergency naloxone to prevent heroin overdose deaths after prison release: rationale and practicalities for the N-ALIVE randomized trial.出狱后携带急救纳洛酮预防海洛因过量死亡:N-ALIVE 随机试验的原理和实用性。
J Urban Health. 2013 Oct;90(5):983-96. doi: 10.1007/s11524-013-9803-1.
10
Evaluation of an Opiate Overdose Educational Intervention and Naloxone Prescribing Program in Homeless Adults Who Use Opiates.对使用阿片类药物的无家可归成年人进行阿片类药物过量教育干预和纳洛酮处方计划的评估。
J Addict Nurs. 2018 Jul/Sep;29(3):188-195. doi: 10.1097/JAN.0000000000000235.

引用本文的文献

1
"I don't let anybody die on my watch": perspectives on the intersection of community overdose response and emergency medical services among people who use drugs in Seattle, WA.“在我的任期内,我不会让任何人死去”:华盛顿州西雅图市吸毒者对社区过量用药应对与紧急医疗服务交叉点的看法。
Harm Reduct J. 2025 Mar 28;22(1):43. doi: 10.1186/s12954-025-01193-0.
2
Patterns of socioeconomic marginalization and non-fatal overdose among people who use drugs: A gender-stratified repeated measures latent class analysis.吸毒人群中的社会经济边缘化模式与非致命性药物过量:一项性别分层重复测量潜在类别分析。
Soc Sci Med. 2025 Feb;366:117661. doi: 10.1016/j.socscimed.2024.117661. Epub 2024 Dec 22.
3
A systematic review of the distribution of take-home naloxone in low- and middle-income countries and barriers to the implementation of take-home naloxone programs.在中低收入国家中,将纳洛酮带回家的分布情况的系统评价以及将纳洛酮带回家方案实施的障碍。
Harm Reduct J. 2022 Oct 20;19(1):117. doi: 10.1186/s12954-022-00700-x.
4
Emotional reactions of trained overdose responders who use opioids following intervention in an overdose event.在干预过量用药事件后使用阿片类药物的训练有素的过量用药反应者的情绪反应。
Subst Abus. 2022;43(1):581-591. doi: 10.1080/08897077.2021.1975870. Epub 2021 Sep 14.
5
Stakeholders' Perceptions of Factors Influencing the Use of Take-Home-Naloxone.利益相关者对影响使用纳洛酮带回家计划因素的看法。
Pharmacy (Basel). 2020 Dec 3;8(4):232. doi: 10.3390/pharmacy8040232.
6
Factors associated with withdrawal symptoms and anger among people resuscitated from an opioid overdose by take-home naloxone: Exploratory mixed methods analysis.通过带回家的纳洛酮从阿片类药物过量中复苏的人群中与戒断症状和愤怒相关的因素:探索性混合方法分析。
J Subst Abuse Treat. 2020 Oct;117:108099. doi: 10.1016/j.jsat.2020.108099. Epub 2020 Aug 5.
7
Provision of peer support at the intersection of homelessness and problem substance use services: a systematic 'state of the art' review.为无家可归和有问题物质使用服务的人提供同伴支持:系统的“最先进”综述。
BMC Public Health. 2020 May 7;20(1):641. doi: 10.1186/s12889-020-8407-4.
8
Common trust and personal safety issues: A systematic review on the acceptability of health and social interventions for persons with lived experience of homelessness.常见的信任和个人安全问题:对有过无家可归经历者的健康和社会干预措施可接受性的系统评价。
PLoS One. 2019 Dec 30;14(12):e0226306. doi: 10.1371/journal.pone.0226306. eCollection 2019.
9
Naloxone dosage for opioid reversal: current evidence and clinical implications.用于阿片类药物逆转的纳洛酮剂量:当前证据及临床意义
Ther Adv Drug Saf. 2018 Jan;9(1):63-88. doi: 10.1177/2042098617744161. Epub 2017 Dec 13.
10
Why are some people who have received overdose education and naloxone reticent to call Emergency Medical Services in the event of overdose?为什么一些接受了过量用药教育和纳洛酮治疗的人在发生过量用药时不愿意拨打急救医疗服务?
Int J Drug Policy. 2017 Oct;48:115-124. doi: 10.1016/j.drugpo.2017.06.008. Epub 2017 Jul 19.

本文引用的文献

1
Drug users' experiences of witnessing overdoses: what do they know and what do they need to know?吸毒者目睹用药过量的经历:他们知道什么,又需要知道什么?
Drug Alcohol Rev. 2000 Dec;19(4):407-412. doi: 10.1080/713659420.
2
Exploring the relationship between homelessness and risk factors for heroin-related death--a qualitative study.探究无家可归与海洛因相关死亡风险因素之间的关系——一项定性研究。
Drug Alcohol Rev. 2005 May;24(3):245-51. doi: 10.1080/09595230500170308.
3
The prescribing of methadone and other opioids to addicts: national survey of GPs in England and Wales.向成瘾者开具美沙酮及其他阿片类药物的情况:英格兰和威尔士全科医生全国调查
Br J Gen Pract. 2005 Jun;55(515):444-51.
4
Making decisions about benefits and harms of medicines.对药物的益处和危害做出决策。
BMJ. 2004 Jul 3;329(7456):47-50. doi: 10.1136/bmj.329.7456.47.
5
Perception of risks.风险认知
Toxicol Lett. 2004 Apr 1;149(1-3):405-13. doi: 10.1016/j.toxlet.2003.12.051.
6
Homelessness and primary care.无家可归与初级医疗保健。
Br J Gen Pract. 2003 Jul;53(492):568-9.
7
Data on take home naloxone are unclear but not condemnatory.关于带回家的纳洛酮的数据不明确,但并非谴责性的。
BMJ. 2002 Mar 16;324(7338):678. doi: 10.1136/bmj.324.7338.678.
8
A prospective study of mortality among drug misusers during a 4-year period after seeking treatment.一项关于吸毒者在寻求治疗后4年期间死亡率的前瞻性研究。
Addiction. 2002 Jan;97(1):39-47. doi: 10.1046/j.1360-0443.2002.00079.x.
9
Understanding risk and lessons for clinical risk communication about treatment preferences.理解风险以及关于治疗偏好的临床风险沟通的经验教训。
Qual Health Care. 2001 Sep;10 Suppl 1(Suppl 1):i9-13. doi: 10.1136/qhc.0100009...
10
Predictors of accidental fatal drug overdose among a cohort of injection drug users.一组注射吸毒者中意外致命药物过量的预测因素。
Am J Public Health. 2001 Jun;91(6):984-7. doi: 10.2105/ajph.91.6.984.