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一例良性转移性平滑肌瘤伴软组织、骨骼肌、肺和乳腺多发转移。

A case of benign metastasizing leiomyoma with multiple metastasis to the soft tissue, skeletal muscle, lung and breast.

作者信息

Jo Ji Hoon, Lee Jin Hwa, Kim Dae Cheol, Kim Sung Hyun, Kwon Hyuk Chan, Kim Jae Seok, Kim Hyo Jin

机构信息

Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.

出版信息

Korean J Intern Med. 2006 Sep;21(3):199-201. doi: 10.3904/kjim.2006.21.3.199.

DOI:10.3904/kjim.2006.21.3.199
PMID:17017672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3890726/
Abstract

Benign metastasizing leiomyoma (BML) is composed of well-differentiated smooth muscle cells and dense connective tissue. BML affects middle-aged women who have had previous hysterectomies due to a histologically benign-appearing uterine leiomyoma. We report here on a case of BML from the uterine leiomyoma in a 39-year-old woman that involved the soft tissues, skeletal muscles, lungs and breasts. She underwent a hysterectomy for the uterine leiomyoma, double oophorectomy for hormonal ablation and lung wedge resection to confirm the diagnosis. The microscopic findings of the breast and lung tumor were similar to those of the benign uterine leiomyoma. Therefore, we consider that these lesions were breast and pulmonary metastases of the uterine leiomyoma. We report here on a rare case of benign metastasizing uterine leiomyoma that involved the soft tissue, skeletal muscles, lungs and breasts, and we include a review of the relevant literature.

摘要

良性转移性平滑肌瘤(BML)由分化良好的平滑肌细胞和致密结缔组织组成。BML影响中年女性,这些女性因组织学上表现为良性的子宫平滑肌瘤而先前接受过子宫切除术。我们在此报告一例39岁女性子宫平滑肌瘤发生的BML病例,其累及软组织、骨骼肌、肺和乳房。她因子宫平滑肌瘤接受了子宫切除术,因激素消融接受了双侧卵巢切除术,并接受了肺楔形切除术以确诊。乳房和肺部肿瘤的显微镜检查结果与良性子宫平滑肌瘤相似。因此,我们认为这些病变是子宫平滑肌瘤的乳房和肺部转移灶。我们在此报告一例罕见的良性转移性子宫平滑肌瘤病例,其累及软组织、骨骼肌、肺和乳房,并对相关文献进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29ab/3890726/93352df8621d/kjim-21-199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29ab/3890726/eab8553498e0/kjim-21-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29ab/3890726/93352df8621d/kjim-21-199-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29ab/3890726/eab8553498e0/kjim-21-199-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29ab/3890726/93352df8621d/kjim-21-199-g002.jpg

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引用本文的文献

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Diseases. 2024 Aug 11;12(8):181. doi: 10.3390/diseases12080181.
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Pulmonary benign metastasizing uterine leiomyoma (PBML): a case report and review of the literature.肺良性转移性子宫平滑肌瘤(PBML):一例病例报告及文献复习
Ann Med Surg (Lond). 2023 Jun 7;85(7):3686-3691. doi: 10.1097/MS9.0000000000000884. eCollection 2023 Jul.
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本文引用的文献

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Benign metastasizing leiomyoma of the uterus: histologic and immunohistochemical characterization of primary and metastatic lesions.子宫良性转移性平滑肌瘤:原发灶和转移灶的组织学及免疫组化特征
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BMC Womens Health. 2023 Apr 1;23(1):154. doi: 10.1186/s12905-023-02237-y.
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