Schloss Patrick D, Handelsman Jo
Department of Plant Pathology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Appl Environ Microbiol. 2006 Oct;72(10):6773-9. doi: 10.1128/AEM.00474-06.
The recent advent of tools enabling statistical inferences to be drawn from comparisons of microbial communities has enabled the focus of microbial ecology to move from characterizing biodiversity to describing the distribution of that biodiversity. Although statistical tools have been developed to compare community structures across a phylogenetic tree, we lack tools to compare the memberships and structures of two communities at a particular operational taxonomic unit (OTU) definition. Furthermore, current tests of community structure do not indicate the similarity of the communities but only report the probability of a statistical hypothesis. Here we present a computer program, SONS, which implements nonparametric estimators for the fraction and richness of OTUs shared between two communities.
近期出现的能够从微生物群落比较中得出统计推断的工具，使得微生物生态学的重点从表征生物多样性转移到描述该生物多样性的分布。尽管已经开发出统计工具来比较系统发育树上的群落结构，但我们缺乏在特定操作分类单元（OTU）定义下比较两个群落的成员和结构的工具。此外，当前的群落结构测试并未表明群落的相似性，而只是报告统计假设的概率。在此，我们展示了一个计算机程序SONS，它实现了用于估计两个群落之间共享的OTU比例和丰富度的非参数估计器。
