大肠杆菌磷酸烯醇丙酮酸：糖磷酸转移酶系统酶I突变体中琥珀酸利用的遗传分析。
Genetic analysis of succinate utilization in enzyme I mutants of the phosphoenolpyruvate: sugar phosphotransferase system in Escherichia coli.
作者信息
Alexander J K, Tyler B
出版信息
J Bacteriol. 1975 Oct;124(1):252-61. doi: 10.1128/jb.124.1.252-261.1975.
Abstract
Studies on the reversion characteristics of Escherichia coli strains carrying various mutations in the pts region have led to the recognition of a mutation, suc-1, with a previously undescribed phenotype. Strains carrying the suc-1 mutation grow normally on most sources of carbon but are unable to utilize succinate effectively. The suc-1 mutation can be separated genetically from the tightly linked ptsI6 mutation. Reversion of suc-1 mutants for growth on succinate yields interesting classes of suppressor mutations.
摘要
对在磷酸烯醇式丙酮酸
糖磷酸转移酶系统（pts）区域携带各种突变的大肠杆菌菌株的回复突变特性研究，已导致识别出一种具有先前未描述表型的突变，即suc-1。携带suc-1突变的菌株在大多数碳源上能正常生长，但不能有效利用琥珀酸盐。suc-1突变可通过遗传学方法与紧密连锁的ptsI6突变分离。suc-1突变体在琥珀酸盐上生长的回复突变产生了有趣的抑制突变类别。
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