大肠杆菌的分解代谢物阻遏基因。
Catabolite repression gene of Escherichia coli.
作者信息
Tyler B, Wishnow R, Loomis W F, Magasanik B
出版信息
J Bacteriol. 1969 Nov;100(2):809-16. doi: 10.1128/jb.100.2.809-816.1969.
Abstract
A catabolite repression gene (cat) which alters the sensitivity of Escherichia coli to catabolite repression has been mapped by transduction and shown to be located between the pyrC and purB genes. When the cat-1 mutation was studied in a number of genetic backgrounds, the results showed that this mutation affects the synthesis of more than one catabolic enzyme but does not completely eliminate catabolic repression under all conditions. It is suggested that this mutation may cause a block in the accumulation of the catabolite effector. Our experiments show that this effector is not glucose-6-phosphate.
摘要
一个改变大肠杆菌对分解代谢物阻遏敏感性的分解代谢物阻遏基因（cat）已通过转导进行定位，结果表明它位于pyrC和purB基因之间。当在多种遗传背景下研究cat-1突变时，结果显示该突变影响不止一种分解代谢酶的合成，但在所有条件下并未完全消除分解代谢物阻遏。有人提出，这种突变可能导致分解代谢物效应物的积累受阻。我们的实验表明，这种效应物不是6-磷酸葡萄糖。
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Nature of the effector of catabolite repression of beta-galactosidase in Escherichia coli.大肠杆菌中β-半乳糖苷酶分解代谢物阻遏效应物的性质
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