Augot D, Muller D, Demerson J M, Boué F, Caillot C, Cliquet F
AFSSA Nancy, laboratoire d'études et de recherches sur la rage et la pathologie des animaux sauvages, WHO/OIE Collaborating centre for research and management in zoonoses control, 54220 Malzéville cedex, France.
Pathol Biol (Paris). 2006 Dec;54(10):572-7. doi: 10.1016/j.patbio.2006.07.039. Epub 2006 Oct 5.
The hantaviruses (genus Hantavirus, family Bunyaviridae) include human pathogens and occur worldwide. In Western and Central Europe, the predominant serotype is Puumala (PUU) virus, which causes epidemic nephropathy. Voles are considered to be the main reservoir and the vector of PUU virus. A total of 719 rodents (mainly Clethrionomys glareolus, Apodemus sp.) trapped by capture-mark-recapture (CMR) in four sites in Ardennes department (France) between April 2004 and October 2005 were tested for the presence of PUU virus antibodies by enzyme-linked immunosorbent assay (ELISA). The predominant species, C. glareolus (86.5% [622 of 719]), also had the highest antibody prevalence (37.6% [291 of 773]). In C. glareolus, the antibody prevalence rate increased with age (weight) in site A, B and D, reaching more than 50% in the heaviest weight, and suggesting that horizontal infection may be important.
汉坦病毒（汉坦病毒属，布尼亚病毒科）包括人类病原体，在全球范围内均有出现。在西欧和中欧，主要的血清型是普马拉（PUU）病毒，它会引发流行性肾病。田鼠被认为是PUU病毒的主要宿主和传播媒介。2004年4月至2005年10月期间，在法国阿登省四个地点通过标记重捕法（CMR）捕获的719只啮齿动物（主要是棕背䶄、姬鼠属），采用酶联免疫吸附测定法（ELISA）检测其是否存在PUU病毒抗体。主要物种棕背䶄（占719只中的622只，即86.5%）的抗体阳性率也最高（占773只中的291只，即37.6%）。在棕背䶄中，A、B和D地点的抗体阳性率随年龄（体重）增加，在体重最重的组中达到50%以上，这表明水平感染可能很重要。
