Aksoy Alev, Duran Nizami, Toroglu Serdar, Koksal Fatih
Department of Orthodontics, Süleyman Demirel University, Isparta, Turkey.
Angle Orthod. 2007 Jan;77(1):124-8. doi: 10.2319/122205-455R.1.
To determine antibacterial activity of chewing mastic gum against the salivary levels of Streptococcus mutans, the total number of viable bacteria, and lactobacilli in patients undergoing therapy with fixed orthodontic appliances.
In this study, the levels of S mutans, lactobacilli, and total cultivated bacteria were measured before and after chewing mastic gum. The antibacterial effects of chewing mastic gum against these microorganisms in saliva were compared with a placebo gum. The counts for orthodontically treated patients were evaluated before chewing gum; just after chewing gum; and after 45, 75, 105, and 135 minutes. Saliva samples taken from the patients were inoculated onto trypticase-yeast-cystine-bacitracin agar for mutans streptococci and onto Rogosa agar for lactobacilli. The agar plates were incubated for 48 hours anaerobically at 37 degrees C. The total number of viable bacteria was then counted.
Just after chewing the mastic gum for 15 minutes, a significant decrease of total bacteria and S mutans was observed (P < .001). The reduction in lactobacilli was not significant at later first stage (P > .05). However, at the end of 135 minutes, there were significantly fewer S mutans (P < .001), total viable bacteria (P < .001), and lactobacilli (P < .001) in the oral cavity after chewing mastic gum than after chewing paraffin (P < .001). The results show that chewing mastic gum decreased the total viable bacteria, S mutans, and lactobacilli in saliva in orthodontically treated patients with fixed appliances.
Chewing mastic gum might be useful in preventing caries lesions.
确定咀嚼乳香口香糖对接受固定正畸矫治器治疗患者唾液中变形链球菌水平、活菌总数及乳酸菌的抗菌活性。
在本研究中，测量了咀嚼乳香口香糖前后变形链球菌、乳酸菌及总培养细菌的水平。将咀嚼乳香口香糖对唾液中这些微生物的抗菌效果与安慰剂口香糖进行比较。对正畸治疗患者在咀嚼口香糖前、刚咀嚼完口香糖时以及咀嚼后45、75、105和135分钟时进行计数评估。从患者采集的唾液样本接种到用于变形链球菌的胰蛋白酶 - 酵母 - 胱氨酸 - 杆菌肽琼脂和用于乳酸菌的罗戈萨琼脂上。琼脂平板在37℃厌氧培养48小时。然后计算活菌总数。
咀嚼乳香口香糖15分钟后，观察到总细菌和变形链球菌显著减少（P <.001）。在最初阶段乳酸菌的减少不显著（P >.05）。然而，在135分钟结束时，咀嚼乳香口香糖后口腔中的变形链球菌（P <.001）、活菌总数（P <.001）和乳酸菌（P <.001）比咀嚼石蜡后显著减少（P <.001）。结果表明，咀嚼乳香口香糖可降低接受固定矫治器正畸治疗患者唾液中的活菌总数、变形链球菌和乳酸菌。
咀嚼乳香口香糖可能有助于预防龋损。
