Milia Egle Patrizia, Sardellitti Luigi, Eick Sigrun
Department of Medicine, Surgery and Pharmacy, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy.
Dental Unit, Azienda Ospedaliero-Universitaria di Sassari, 07100 Sassari, Italy.
Microorganisms. 2023 May 24;11(6):1378. doi: 10.3390/microorganisms11061378.
L. (PlL) has been used for centuries in traditional medicine. The richness in antimicrobial biomolecules of Pll derivates can represent an alternative to chemically formulated agents used against oral infections. This review summarizes the knowledge on the antimicrobial activity of PlL essential oil (EO), extracts, and mastic resin against microorganisms being of relevance in oral biofilm-associated diseases. Results demonstrated that the potential of PlL polyphenol extracts has led to increasing scientific interest. In fact, the extracts are a significantly more effective agent than the other PlL derivates. The positive findings regarding the inhibition of periodontal pathogens and , together with the antioxidant activity and the reduction of the inflammatory responses, suggest the use of the extracts in the prevention and/or reversal of intraoral dysbiosis. Toothpaste, mouthwashes, and local delivery devices could be effective in the clinical management of these oral diseases.
乳香（PlL）在传统医学中已使用了数百年。乳香衍生物中丰富的抗菌生物分子可以替代用于对抗口腔感染的化学制剂。本综述总结了关于乳香精油（EO）、提取物和乳香树脂对与口腔生物膜相关疾病相关的微生物的抗菌活性的知识。结果表明，乳香多酚提取物的潜力引起了越来越多的科学关注。事实上，提取物比其他乳香衍生物更有效。关于抑制牙周病原体的积极发现，以及抗氧化活性和炎症反应的减轻，表明提取物可用于预防和/或逆转口腔内生态失调。牙膏、漱口水和局部给药装置可能对这些口腔疾病的临床管理有效。
