Tabak H F, Hoepfner D, Zand A v d, Geuze H J, Braakman I, Huynen M A
Department of Cellular Protein Chemistry, University of Utrecht, Padualaan 8, NL-3548 CH Utrecht, The Netherlands.
Biochim Biophys Acta. 2006 Dec;1763(12):1647-54. doi: 10.1016/j.bbamcr.2006.08.045. Epub 2006 Sep 3.
Eukaryotic cells contain functionally distinct, membrane enclosed compartments called organelles. Here we like to address two questions concerning this architectural lay out. How did this membrane complexity arise during evolution and how is this collection of organelles maintained in multiplying cells to ensure that new cells retain a complete set of them. We will try to address these questions with peroxisomes as a focal point of interest.
真核细胞包含功能各异、被膜包裹的区室，即细胞器。在此，我们想探讨关于这种结构布局的两个问题。在进化过程中，这种膜的复杂性是如何产生的，以及在细胞增殖过程中，这一系列细胞器是如何得以维持，以确保新细胞保留一整套细胞器。我们将以过氧化物酶体为重点来尝试探讨这些问题。
