Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, United States.
The Laboratory of Cell and Molecular Biology, NIDDK, NIH, Bethesda, MD 20892, United States.
Curr Opin Cell Biol. 2014 Feb;26:79-86. doi: 10.1016/j.ceb.2013.10.006. Epub 2013 Nov 16.
The cell interior is a busy and crowded place. A large fraction of the cell volume is taken up by organelles that come in a variety of shapes and sizes. These organelles are surrounded by membrane that not only acts as a diffusion barrier, but also provides each organelle with its unique morphology that contributes to its function, often in ways that are poorly understood. Here we discuss recent discoveries on the relationship between organelle structure and function.
细胞内部是一个繁忙而拥挤的地方。细胞体积的很大一部分被各种形状和大小的细胞器占据。这些细胞器被膜包围,膜不仅起到扩散屏障的作用,还赋予每个细胞器独特的形态,这有助于其功能,而这些功能往往还不太为人理解。在这里,我们讨论了细胞器结构与功能之间关系的最新发现。