Yamamoto T
Department of Dermatology, Tokyo Medical University, 6-7-1 Nishishinjuku, Tokyo 160-0023, Japan.
Br J Dermatol. 2006 Nov;155(5):869-75. doi: 10.1111/j.1365-2133.2006.07474.x.
Bleomycin is frequently used as a chemotherapeutic agent to treat various kinds of malignancy. However, the cytotoxic effects of bleomycin cause a number of adverse responses, in particular in the lung and the skin. Bleomycin is used by dermatologists as a treatment for various skin cancers, recalcitrant warts, keloid and hypertrophic scars. This article discusses the use of bleomycin for various skin disorders, as well as the risk factors and cutaneous side-effects resulting from its use.
博来霉素常被用作化疗药物来治疗各种恶性肿瘤。然而，博来霉素的细胞毒性作用会引发多种不良反应，尤其是在肺部和皮肤。皮肤科医生使用博来霉素治疗各种皮肤癌、顽固性疣、瘢痕疙瘩和增生性瘢痕。本文讨论了博来霉素在各种皮肤疾病中的应用，以及使用该药的风险因素和皮肤副作用。
