de Boer Michiel R, Twisk Jos, Moll Annette C, Völker-Dieben Hennie J M, de Vet Henrica C W, van Rens Ger H M B
Department of Ophthalmology, VU University Medical Center, Amsterdam, The Netherlands.
Ophthalmic Physiol Opt. 2006 Nov;26(6):535-44. doi: 10.1111/j.1475-1313.2006.00424.x.
Consecutive patients (n = 215) who were referred to optometric (55%) or multidisciplinary (45%) low-vision services and above 50 years of age were recruited from four hospitals in the Netherlands. They completed two vision-related quality of life questionnaires, the Vision Quality of Life Core Measure (VCM1) and the Low Vision Quality of Life Questionnaire (LVQOL), before their first visit with low-vision services and 1 year later. At follow-up, patients referred to multidisciplinary low-vision services had lower scores on the mobility subscale of the LVQOL than patients referred to optometric low-vision services [5.3 points; 95% confidence interval (CI): 0.2-10.5]. Paired sample t-tests for the two groups of patients taken together show improvement for the VCM1 (3.1 points; 95% CI: 0.6-5.6) and deterioration for the basic aspects of vision (3.5 points; 95% CI: 1.1-5.9) and the mobility (6.6 points; 95% CI: 3.7-9.5) subscales of the LVQOL. In conclusion, people referred to optometric services showed less deterioration in mobility than those referred to multidisciplinary services. No differences were observed for any of the other subscales of the LVQOL and the VCM1. Future research in this field should include randomized controlled designs comparing low-vision services with no treatment or placebo.
连续入选了215名来自荷兰四家医院、年龄在50岁及以上、被转介至验光(55%)或多学科(45%)低视力服务机构的患者。他们在首次就诊于低视力服务机构之前和1年后分别完成了两份与视力相关的生活质量问卷,即视力生活质量核心量表(VCM1)和低视力生活质量问卷(LVQOL)。在随访时,被转介至多学科低视力服务机构的患者在LVQOL的活动能力子量表上的得分低于被转介至验光低视力服务机构的患者[5.3分;95%置信区间(CI):0.2 - 10.5]。对两组患者进行的配对样本t检验显示,VCM1有改善(3.1分;95% CI:0.6 - 5.6),而LVQOL的视力基本方面(3.5分;95% CI:1.1 - 5.9)和活动能力(6.6分;95% CI:3.7 - 9.5)子量表有恶化。总之,被转介至验光服务机构的患者在活动能力方面的恶化程度低于被转介至多学科服务机构的患者。在LVQOL和VCM1的任何其他子量表上均未观察到差异。该领域未来的研究应包括比较低视力服务与不治疗或安慰剂的随机对照设计。