Shirani Shapour, Boroumand Mohammad Ali, Abbasi Seyed Hesameddin, Maghsoodi Negar, Shakiba Madjid, Karimi Abbasali, Davoodi Saeed, Esfandbod Maryam
Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Arch Med Res. 2006 Nov;37(8):987-90. doi: 10.1016/j.arcmed.2006.06.001.
The incidence of stroke is 2.1-5.2% in bypass surgery patients with a mortality of 0-38%. This study was designed to evaluate the incidence of significant carotid artery stenosis and its related risk factors in candidates for coronary artery bypass graft (CABG) surgery.
One thousand forty five consecutive candidates for CABG underwent carotid artery Doppler examination in a prospective study. The relation of age, sex, smoking and diabetes history, as well as lipid profile with carotid stenosis, was evaluated.
In 1045 CABG candidates with a mean age of 60 years, prevalence of significant carotid stenosis (>60%) was 6.9%. In the patients aged 65 years and older, the rate of significant stenosis was 12.5%. Age >50 years, female gender, hypercholesterolemia and diabetes mellitus are independent risk factors for significant carotid stenosis.
Significant carotid stenosis has an earlier appearance in our study. Cost-effectiveness studies are recommended for revising the previous screening protocols.
在接受搭桥手术的患者中，中风发生率为2.1%-5.2%，死亡率为0%-38%。本研究旨在评估冠状动脉搭桥术（CABG）候选患者中显著颈动脉狭窄的发生率及其相关危险因素。
在一项前瞻性研究中，对1045例连续的CABG候选患者进行了颈动脉多普勒检查。评估了年龄、性别、吸烟和糖尿病史以及血脂谱与颈动脉狭窄的关系。
在平均年龄为60岁的1045例CABG候选患者中，显著颈动脉狭窄（>60%）的患病率为6.9%。在65岁及以上的患者中，显著狭窄率为12.5%。年龄>50岁、女性、高胆固醇血症和糖尿病是显著颈动脉狭窄的独立危险因素。
在我们的研究中，显著颈动脉狭窄出现得更早。建议进行成本效益研究以修订先前的筛查方案。
