Byrne A R, Versieck J
J. Stefan Institute, E. Kardelj University, Ljubljana, Yugoslavia.
Biol Trace Elem Res. 1990 Jul-Dec;26-27:529-40. doi: 10.1007/BF02992709.
In order to help resolve present inconsistencies of two orders of magnitude or more in reported levels of vanadium in human serum and blood, a totally postirradiation radiochemical neutron activation analysis (NAA) method was further developed and applied to some pertinent nanogram and subnanogram reference materials. In particular, the second generation human serum reference material of Versieck was found to contain a value of 0.67 +/- 0.05 ng/g dry wt., corresponding to 0.061 +/- 0.005 /4/ ng/mL original fresh serum. Results are also reported for some other appropriate CRMs. Additionally, a small-scale study in 10 normal subjects (5 m, 5 f) revealed levels similar to those in the serum reference material and in agreement with the lowest data reported in the literature. Discussion of pitfalls of vanadium determination and the use of reference materials is included.
为了帮助解决目前人类血清和血液中钒含量报告存在两个数量级或更多的不一致问题，进一步开发了一种完全辐照后放射化学中子活化分析（NAA）方法，并将其应用于一些相关的纳克和亚纳克参考物质。特别是，发现Versieck的第二代人血清参考物质的值为0.67±0.05 ng/g干重，相当于0.061±0.005 /4/ ng/mL原始新鲜血清。还报告了其他一些合适的有证参考物质的结果。此外，对10名正常受试者（5名男性，5名女性）的小规模研究显示，其水平与血清参考物质中的水平相似，并且与文献中报告的最低数据一致。文中还讨论了钒测定的陷阱以及参考物质的使用。
