Wang Shang-Kwei, Huang Min-Jay, Duh Chang-Yih
Department of Microbiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China.
J Nat Prod. 2006 Oct;69(10):1411-6. doi: 10.1021/np0601253.
Three new cytotoxic dolabellane diterpenes, 1-3, three new aromandendrane sesquiterpenoids, 4-6, a new sesquiterpene, 7 (having a new carbon skeleton), and a new cytotoxic xenicane diterpene, 8, were isolated from the methylene chloride solubles of the Formosan soft coral Clavularia inflata var. luzoniana. The structures were elucidated by extensive spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
从台湾软珊瑚吕宋泡囊软珊瑚（Clavularia inflata var. luzoniana）的二氯甲烷可溶部分中分离得到了三种新的具有细胞毒性的多拉贝拉烷二萜（1 - 3）、三种新的芳满烷倍半萜（4 - 6）、一种新的倍半萜（7，具有新的碳骨架）以及一种新的具有细胞毒性的异香树烷二萜（8）。通过广泛的光谱分析阐明了它们的结构，并在体外测定了它们对选定癌细胞的细胞毒性。
