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金黄色葡萄球菌中低水平抗生素耐药性的潜在临床影响。

The potential clinical impact of low-level antibiotic resistance in Staphylococcus aureus.

作者信息

Goldstein F

机构信息

Hospital Saint-Joseph, 185 rue Raymond Losserand, 75014 Paris, France.

出版信息

J Antimicrob Chemother. 2007 Jan;59(1):1-4. doi: 10.1093/jac/dkl429. Epub 2006 Oct 26.

DOI:10.1093/jac/dkl429
PMID:17068009
Abstract

Low-level antibiotic resistance in Staphylococcus aureus is a frequently overlooked phenomenon, usually not detected by standard susceptibility testing procedures. It represents a gateway to high-level clinically relevant resistance. Moreover, low-level resistance may be associated with increased virulence, resistance to unrelated compounds and more successful in vivo survival.

摘要

金黄色葡萄球菌中的低水平抗生素耐药性是一种经常被忽视的现象，通常无法通过标准药敏试验程序检测到。它是通向高水平临床相关耐药性的一个途径。此外，低水平耐药性可能与毒力增加、对无关化合物的耐药性以及在体内更成功的存活有关。

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