Department of Clinical Bacteriology, Provincial Hospital of Koszalin, Koszalin, Poland.
Mol Diagn Ther. 2010 Apr 1;14(2):73-80. doi: 10.1007/BF03256356.
Methicillin-resistant Staphylococcus aureus (MRSA) is a common pathogen responsible for a wide spectrum of healthcare-associated and community-acquired infections. Infections with MRSA strains that are resistant to beta-lactams and other types of antibiotics are a serious therapeutic problem - first, because in such cases only a limited spectrum of antibiotics can be used; and second, because such infections require prolonged hospitalization and result in economic losses. Therefore, in order to limit the overspread of pathogens, the development of diagnostic tools enabling rapid identification of carriers and infected patients, as well as proper identification of drug-resistance mechanisms to enable development of more targeted clinical treatment, are vital. This article reviews the current knowledge concerning prospective diagnostics of MRSA infections.
耐甲氧西林金黄色葡萄球菌（MRSA）是一种常见的病原体，可引起广泛的医疗保健相关和社区获得性感染。对耐β-内酰胺类抗生素和其他类型抗生素的 MRSA 菌株的感染是一个严重的治疗问题——首先，因为在这种情况下只能使用有限的抗生素谱；其次，因为这种感染需要长时间住院治疗，并导致经济损失。因此，为了限制病原体的传播，开发能够快速识别携带者和感染患者的诊断工具，以及正确识别耐药机制以开发更有针对性的临床治疗方法至关重要。本文综述了有关 MRSA 感染的前瞻性诊断的现有知识。
