Low Bee Yean, Liong Men Long, Yuen Kah Hay, Chong Wooi Loong, Chee Christopher, Leong Wing Seng, Teh Chu Leong, Karim Nurzalina, Yap Hin Wai, Cheah Phaik Yeong
School of Pharmaceutical Sciences, University of Science Malaysia, Penang, Malaysia.
Urology. 2006 Oct;68(4):751-8. doi: 10.1016/j.urology.2006.05.021.
To determine the prevalence, severity, and quality-of-life (QOL) impact of female lower urinary tract symptoms (FLUTS); to determine the patterns, reasons, and factors contributing to the women's treatment-seeking behavior; and to describe the relationship between the social demographic characteristics and FLUTS.
A total of 2732 women older than 19 years of age were recruited by a series of FLUTS Awareness Campaigns held within Northern Malaysia from January to August 2004. Trained interviewers used surveys to collect information on social demographic characteristics, International Prostate Symptom Score, and King's Health Questionnaire to determine the prevalence, severity, QOL impact, treatment-seeking behavior, and risk factors of FLUTS.
The prevalence of FLUTS was 19.0% (n = 519), with 88.6% having moderate and 11.4% severe FLUTS. Using the International Prostate Symptom Score QOL assessment index, 55.3% (n = 287) scored 4 or greater. Using the King's Health Questionnaire, the most affected QOL domain was sleep/energy. The patterns of treatment-seeking behavior revealed that only 23.1% (n = 120) of patients with FLUTS actively sought treatment. The major reason for those (76.9%) who failed to seek treatment was that they did not perceive FLUTS as a major health problem (29.1%). Factors that warranted treatment were the severity, bother, and QOL impact of FLUTS (all P <0.001), hematuria (P <0.001), age (P <0.005), parity, body mass index, and suprapubic pain (all P <0.05). The risk factors for FLUTS (defined as an odds ratio of 2 or more) included age 50 years or older, parity of 4 or more, illiteracy, postmenopausal status, and the presence of one or more concomitant chronic medical illness.
Despite the high prevalence of FLUTS in Northern Malaysia (19.0%), many patients do not seek treatment, with ignorance being the major reason.
确定女性下尿路症状（FLUTS）的患病率、严重程度及对生活质量（QOL）的影响；确定女性寻求治疗行为的模式、原因及相关因素；描述社会人口统计学特征与FLUTS之间的关系。
通过2004年1月至8月在马来西亚北部开展的一系列FLUTS宣传活动，招募了总共2732名19岁以上的女性。经过培训的访谈者使用调查问卷收集社会人口统计学特征、国际前列腺症状评分以及国王健康问卷的信息，以确定FLUTS的患病率、严重程度、对生活质量的影响、寻求治疗行为及危险因素。
FLUTS的患病率为19.0%（n = 519），其中88.6%为中度FLUTS，11.4%为重度FLUTS。使用国际前列腺症状评分生活质量评估指数，55.3%（n = 287）的得分在4分及以上。使用国王健康问卷，受影响最大的生活质量领域是睡眠/精力。寻求治疗行为的模式显示，只有23.1%（n = 120）的FLUTS患者积极寻求治疗。未寻求治疗的患者（76.9%）的主要原因是他们不认为FLUTS是一个主要的健康问题（29.1%）。需要治疗的因素包括FLUTS的严重程度、困扰程度及对生活质量的影响（均P <0.001）、血尿（P <0.001）、年龄（P <0.005）、产次、体重指数及耻骨上疼痛（均P <0.05）。FLUTS的危险因素（定义为比值比为2或更高）包括50岁及以上、产次为4次及以上、文盲、绝经后状态以及存在一种或多种伴随的慢性疾病。
尽管马来西亚北部FLUTS的患病率较高（19.0%），但许多患者不寻求治疗，主要原因是无知。
