School of Pharmacy, Faculty of Health and Medical Sciences, Taylor's University (Lakeside Campus), Subang Jaya, Malaysia.
Ferring Pharmaceuticals Malaysia & Singapore, Kuala Lumpur, Malaysia.
BMC Urol. 2021 Jun 29;21(1):95. doi: 10.1186/s12894-021-00860-1.
Nocturia is widely prevalent condition with detrimental effects on quality of life and general health. In Malaysia, there is a lack of up-to-date prevalence study on nocturia. This study aimed to investigate the prevalence of nocturia and awareness pertaining to nocturia among Malaysian adults.
A cross-sectional population-based study was conducted among Malaysian adults aged ≥ 18 years old. The data was collected by mixed mode self-administered questionnaire from May 2019 to September 2019. Nocturia was defined as one or more voids at night.
There were a total of 4616 respondents with 74.5% of response rate. The overall prevalence of nocturia among Malaysian adults was found to be 57.3%. In multivariate analysis, respondents aged 31-40 (1.91 [1.52-2.40]) or > 60 years old (2.03 [1.48-2.71]), and those who presented with hypertension (2.84 [2.28-3.53]), diabetes mellitus (1.78 [1.42-2.25]), renal disease (3.58 [1.93-6.63]) or overactive bladder (1.61 [1.10-2.35]) were associated with higher prevalence of nocturia. A significantly lower disease prevalence (p < 0.05) was noted among those aged 41-50 (0.73 [0.59-0.91]), male (0.78 [0.69-0.88]) and Chinese (0.47 [0.30-0.74]) or Indian (0.34 [0.21-0.54]) ethnicities. A total of 37.3% of respondents with nocturia reported that they faced sleeping difficulty about half the time or more after waking up in the middle of night. Those who had ≥ 2 voids per night experienced significantly higher mean bother score than those who had 1 void per night (p < 0.001). Approximately half (56.7%) of all respondents were not aware that night time urination is a medical condition. Only 25.2% of respondents with nocturia had sought medical attention for their nocturia.
The prevalence of nocturia among Malaysian adults is high and strongly influenced by age, sex, race and comorbidities. However, the general awareness pertaining to nocturia being a health issue remains low among Malaysians. The findings also highlighted the impact of nocturia on sleep and the need for nocturia education to better address this disease.
夜尿症是一种普遍存在的疾病，对生活质量和整体健康有不利影响。在马来西亚，关于夜尿症的最新患病率研究还比较缺乏。本研究旨在调查马来西亚成年人夜尿症的患病率和对夜尿症的认知情况。
本研究采用多阶段分层整群随机抽样方法，对马来西亚年龄≥18 岁的成年人进行了横断面人群为基础的研究。2019 年 5 月至 9 月期间，通过混合模式自填式问卷收集数据。夜尿症定义为夜间有一次或多次排尿。
共有 4616 名受访者，应答率为 74.5%。马来西亚成年人夜尿症的总体患病率为 57.3%。多变量分析显示，31-40 岁（1.91[1.52-2.40]）或>60 岁（2.03[1.48-2.71]）、患有高血压（2.84[2.28-3.53]）、糖尿病（1.78[1.42-2.25]）、肾脏疾病（3.58[1.93-6.63]）或膀胱过度活动症（1.61[1.10-2.35]）的受访者夜尿症患病率较高。年龄在 41-50 岁（0.73[0.59-0.91]）、男性（0.78[0.69-0.88]）、华人（0.47[0.30-0.74]）或印度人（0.34[0.21-0.54]）受访者的疾病患病率显著较低（p<0.05）。37.3%有夜尿症的受访者报告说，他们在半夜醒来后有一半或更多的时间睡眠困难。每晚有≥2 次排尿的受访者的平均困扰评分明显高于每晚排尿 1 次的受访者（p<0.001）。大约一半（56.7%）的受访者不知道夜间排尿是一种医疗状况。有夜尿症的受访者中，只有 25.2%曾因夜尿症寻求医疗帮助。
马来西亚成年人的夜尿症患病率较高，且强烈受年龄、性别、种族和合并症的影响。然而，马来西亚人对夜尿症是健康问题的普遍认识仍然较低。研究结果还强调了夜尿症对睡眠的影响，需要进行夜尿症教育以更好地解决这一疾病。
