Dimitrov Georges, Gottrand Frederic
Gastroenterology, hepatology and nutrition Unit, Clinic of Pediatrics, Hopital J de Flandre, CHRU de Lille et Faculte de Medecine, Universite de Lille 2, Lille, France.
World J Gastroenterol. 2006 Oct 21;12(39):6274-9. doi: 10.3748/wjg.v12.i39.6274.
Several clinical reports confirmed that gastric atrophy is a pathology not only limited to adult patients. In pediatrics, it is most often described in association with a H pylori infection but this bacteria does not seem to be the only etiological factor of this preneoplastic state in children. The frequency of gastric atrophy and intestinal metaplasia in children are unknown because they are not systematically sought during upper gastrointestinal endoscopy. The lack of specific histological classification of childrenos gastropathies makes their diagnosis difficult for pathologists. Based on our knowledge to date, we think that it is necessary to describe, in detail, the natural course of this lesion during childhood. A close and prolonged clinical and endoscopic follow-up is important for children with gastric atrophy.
多项临床报告证实，胃萎缩并非仅见于成年患者的一种病理状态。在儿科，胃萎缩最常与幽门螺杆菌感染相关，但这种细菌似乎并非儿童这种肿瘤前状态的唯一病因。儿童胃萎缩和肠化生的发生率尚不清楚，因为在上消化道内镜检查时未对其进行系统排查。儿童胃病缺乏特定的组织学分类，这使得病理学家难以对其做出诊断。基于我们目前所掌握的知识，我们认为有必要详细描述这种病变在儿童时期的自然病程。对于胃萎缩患儿，密切且长期的临床及内镜随访很重要。
