Rebhun J, Madorsky J G, Glovsky M M
Casa Colina Hospital for Rehabilitative Medicine, Pomona, California.
Ann Allergy. 1991 Apr;66(4):335-8.
Complement activity was studied in patients with spinal cord transection. In some sera acute phase reactants: haptoglobin, C-reactive proteins, ceruloplasmin, as well as fibrinogen and fibrin degradation products, and immune complexes were monitored. Complement and acute phase reactants are increased in a majority of patients. Continuing inflammation and release of inflammatory mediators could be responsible for poor healing that commonly occurs in spinal cord injury. Urinary tract and other infections are associated with some but not all of the protein abnormalities. These proinflammatory proteins may contribute to the lack of healing of spinal transection.
对脊髓横断患者的补体活性进行了研究。在一些血清中，监测了急性期反应物：触珠蛋白、C反应蛋白、铜蓝蛋白，以及纤维蛋白原和纤维蛋白降解产物，还有免疫复合物。大多数患者的补体和急性期反应物增加。持续的炎症和炎症介质的释放可能是脊髓损伤中常见的愈合不良的原因。尿路感染和其他感染与部分而非全部蛋白质异常有关。这些促炎蛋白可能导致脊髓横断愈合不良。
