Hallenbeck John, Del Zoppo Gregory, Jacobs Tom, Hakim Antoine, Goldman Stephen, Utz Ursula, Hasan Ahmed
Stroke Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 49 Convent Dr, MSC 4476, Bethesda, MD 20892-4476, USA.
Stroke. 2006 Dec;37(12):3035-42. doi: 10.1161/01.STR.0000248836.82538.ee. Epub 2006 Nov 2.
This workshop examined the opportunities for translational research directed at immune and inflammatory mechanisms. This summary presents the background data in 3 general areas: (1) inflammation and hemostasis in cerebrovascular and cardiovascular disease, (2) immune interactions in the central nervous system and heart, and (3) translation of immune modulation in the brain and heart, all of which supported a consensus derivation of the opportunities for future research in these areas. The summary concludes with 11 recommendations.
本次研讨会探讨了针对免疫和炎症机制开展转化研究的机会。本综述介绍了三个一般领域的背景数据:(1)脑血管和心血管疾病中的炎症与止血,(2)中枢神经系统和心脏中的免疫相互作用,以及(3)大脑和心脏中免疫调节的转化,所有这些都为这些领域未来研究机会的共识推导提供了支持。综述最后提出了11条建议。