Yamashita Ryo, Yamaguchi Raizou, Yuen Keiji, Niwakawa Masashi, Tobisu Kenichi
Division of Urology, Shizuoka Cancer Center, Nagaizumi, Shizuoka, Japan.
Int J Urol. 2006 Nov;13(11):1448-50. doi: 10.1111/j.1442-2042.2006.01569.x.
The case is reported of urothelial carcinoma (clear cell variant) that was diagnosed with useful immunohistochemistry stain. A 70-year-old man, who had undergone left radical nephrectomy for renal cell carcinoma in August 2003 and partial lobectomy for pulmonary metastasis in May 2005, complained of hematuria in June 2005. On evaluation, a papillary pedunculated tumor was detected in the left wall of the urinary bladder. A transurethral resection of the bladder tumor (TUR-Bt) was performed in July 2005. The pathological diagnosis was difficult due to diffuse clear cell appearance. Immunohistochemistry stain showed urothelial carcinoma, not metastasis of the renal cell carcinoma. Finally it was diagnosed as urothelial carcinoma clear cell variant. Urothelial carcinoma has many variants that show a variety of appearances and characteristics. These should be well known before medical therapy is initiated.
报告了一例经有效免疫组化染色诊断的尿路上皮癌（透明细胞变体）病例。一名70岁男性，于2003年8月因肾细胞癌接受了左肾根治性切除术，并于2005年5月因肺转移接受了部分肺叶切除术，2005年6月出现血尿。经评估，在膀胱左壁发现一个带蒂乳头状肿瘤。2005年7月进行了经尿道膀胱肿瘤切除术（TUR-Bt）。由于弥漫性透明细胞表现，病理诊断困难。免疫组化染色显示为尿路上皮癌，而非肾细胞癌转移。最终诊断为尿路上皮癌透明细胞变体。尿路上皮癌有许多变体，表现出各种外观和特征。在开始医学治疗之前，应充分了解这些情况。
