Department of Morphopathology, The Victor Babes University of Medicine and Pharmacy of Timisoara, Timisoara, Romania.
Bosn J Basic Med Sci. 2019 Nov 8;19(4):400-403. doi: 10.17305/bjbms.2019.4182.
The most common histological type of urinary bladder cancer is urothelial carcinoma (UC). In contrast, the clear cell variant of urothelial carcinoma (CCUC) is quite a rare neoplasm. In this study, we report a case of an 81-year-old male, presenting with gross hematuria and acute urinary retention, which was subsequently diagnosed with CCUC at our pathology department. Furthermore, we provide a short systematic review of the literature (PubMed, Scopus, and Science Citation Index) for this rare histopathological entity and a brief discussion about its morphological and immunohistochemical (IHC) characteristics.
最常见的膀胱癌组织学类型是尿路上皮癌(UC)。相比之下,尿路上皮癌的透明细胞变异型(CCUC)是一种相当罕见的肿瘤。在本研究中,我们报告了一例 81 岁男性患者,因肉眼血尿和急性尿潴留就诊,随后在我院病理科诊断为 CCUC。此外,我们还对这一罕见的组织病理学实体进行了简短的文献系统回顾(PubMed、Scopus 和科学引文索引),并对其形态学和免疫组织化学(IHC)特征进行了简要讨论。