• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

与丁丙诺啡相关的持续性恶心和呕吐。

Prolonged nausea and vomiting associated with buprenorphine.

作者信息

Fullerton T, Timm E G, Kolski G B, Bertino J S

机构信息

Department of Pharmacy Services, Mary Imogene Bassett Hospital, Cooperstown, New York 13326.

出版信息

Pharmacotherapy. 1991;11(1):90-3.

PMID:1708499
Abstract

We conducted a trial to evaluate the histamine-releasing characteristics of morphine, meperidine, and buprenorphine when administered intravenously to 20 healthy adults without pain. Substantially more nausea and vomiting occurred with buprenorphine than with the other compounds, and was more intense on ambulation. High-affinity receptor binding may play a role in the long duration of nausea and vomiting after a single dose of this agent.

摘要

我们进行了一项试验，以评估在无疼痛情况下静脉注射吗啡、哌替啶和丁丙诺啡时这三种药物的组胺释放特性。与其他药物相比，丁丙诺啡引起的恶心和呕吐明显更多，且在走动时更为强烈。高亲和力受体结合可能在单次使用该药物后长时间的恶心和呕吐中起作用。

相似文献

1
Prolonged nausea and vomiting associated with buprenorphine.与丁丙诺啡相关的持续性恶心和呕吐。
Pharmacotherapy. 1991;11(1):90-3.
2
Effects of intravenous patient-controlled analgesia with buprenorphine and morphine alone and in combination during the first 12 postoperative hours: a randomized, double-blind, four-arm trial in adults undergoing abdominal surgery.术后12小时内单独及联合使用丁丙诺啡和吗啡静脉自控镇痛的效果：一项针对接受腹部手术的成年人的随机、双盲、四臂试验。
Clin Ther. 2009 Mar;31(3):527-41. doi: 10.1016/j.clinthera.2009.03.018.
3
Prophylactic metoclopramide is unnecessary with intravenous analgesia in the ED.在急诊科进行静脉镇痛时，预防性使用胃复安并无必要。
Am J Emerg Med. 2000 Oct;18(6):653-7. doi: 10.1053/ajem.2000.16293.
4
[Epidural buprenorphine and epidural droperidol for post-operative nausea or vomiting].
Masui. 1997 Jun;46(6):798-802.
5
Gastrointestinal symptoms under opioid therapy: a prospective comparison of oral sustained-release hydromorphone, transdermal fentanyl, and transdermal buprenorphine.阿片类药物治疗下的胃肠道症状：口服缓释氢吗啡酮、透皮芬太尼和透皮丁丙诺啡的前瞻性比较
Eur J Pain. 2009 Aug;13(7):737-43. doi: 10.1016/j.ejpain.2008.09.005. Epub 2008 Oct 31.
6
Dosage-side-effect relationships of morphine and meperidine.吗啡与哌替啶的剂量-副作用关系。
Anesth Analg. 1973 Jul-Aug;52(4):536-41.
7
Morphine induces less nausea than meperidine when administered parenterally.
J Emerg Med. 2004 Oct;27(3):241-3. doi: 10.1016/j.jemermed.2004.04.011.
8
[Analgesic effect and side-effects of buprenorphine in acute coronary heart disease. A randomized double-blind comparison with morphine].[丁丙诺啡在急性冠心病中的镇痛效果及副作用。与吗啡的随机双盲对照研究]
Anasth Intensivther Notfallmed. 1988 Dec;23(6):309-12.
9
Pain relief after major abdominal surgery: a double-blind controlled comparison of sublingual buprenorphine, intramuscular buprenorphine, and intramuscular meperidine.腹部大手术后的疼痛缓解：舌下含服丁丙诺啡、肌肉注射丁丙诺啡和肌肉注射哌替啶的双盲对照比较。
Anesth Analg. 1987 Feb;66(2):142-6.
10
Comparison of buprenorphine with morphine in the treatment of postoperative pain in children.
Anesth Analg. 1988 Mar;67(3):233-9.

引用本文的文献

1
Analgesics and ENT surgery. A clinical comparison of the intraoperative, recovery and postoperative effects of buprenorphine, diclofenac, fentanyl, morphine, nalbuphine, pethidine and placebo given intravenously with induction of anaesthesia.镇痛药与耳鼻喉科手术。静脉注射丁丙诺啡、双氯芬酸、芬太尼、吗啡、纳布啡、哌替啶及安慰剂并诱导麻醉后，对术中、恢复阶段及术后效果的临床比较。
Br J Clin Pharmacol. 1994 Dec;38(6):533-43. doi: 10.1111/j.1365-2125.1994.tb04395.x.
2
Effects of macro- and microcirculatory functions on ceftriaxone concentrations in tissues of patients with stage IV peripheral arterial occlusive disease.大循环和微循环功能对IV期外周动脉闭塞性疾病患者组织中头孢曲松浓度的影响。
Antimicrob Agents Chemother. 1995 Jan;39(1):15-9. doi: 10.1128/AAC.39.1.15.