肯尼亚急性肠胃炎患儿腹泻粪便和恢复粪便的理化特性及菌群

Physicochemical characteristics and flora of diarrhoeal and recovery faeces in children with acute gastro-enteritis in Kenya.

作者信息

Fujita K, Kaku M, Yanagase Y, Ezaki T, Furuse K, Ozawa A, Saidi S M, Sang W K, Waiyaki P G

机构信息

Department of Paediatrics, Asahikawa Medical College, Japan.

出版信息

Ann Trop Paediatr. 1990;10(4):339-45. doi: 10.1080/02724936.1990.11747455.

DOI:10.1080/02724936.1990.11747455

PMID:1708960

Abstract

Physiochemical characteristics and flora of diarrhoeal and recovery faeces were investigated in 14 Kenyan children with acute gastro-enteritis. Causative micro-organisms were Shigella, Campylobacter, enterotoxigenic Escherichia coli, rotavirus and unknown in 6, 2, 1, 2 and 3 patients, respectively. The mean values of the pH of the diarrhoeal specimens were significantly higher than those of the recovery specimens. Large amounts of acetic acid and many other kinds of fatty acids were detected in the recovery specimens, but small amounts and few kinds of fatty acids were detected in the diarrhoeal specimens. Bacterial counts of anaerobic organisms, such as Bacteroides, Bifidobacterium, Lactobacillus and Eubacterium, were lower in the diarrhoeal specimens than in the recovery ones. The normal anaerobic intestinal flora is remarkably disturbed in patients with acute gastro-enteritis. This may result in changes in fatty acid contents and in the pH of diarrhoeal faeces.

摘要

对14名患有急性肠胃炎的肯尼亚儿童腹泻粪便和恢复阶段粪便的理化特性及菌群进行了研究。致病微生物分别为志贺氏菌、弯曲杆菌、产肠毒素大肠杆菌、轮状病毒，6例、2例、1例、2例和3例患者的致病微生物不明。腹泻样本的pH平均值显著高于恢复样本。恢复样本中检测到大量乙酸和许多其他种类的脂肪酸，但腹泻样本中检测到的脂肪酸量少且种类少。腹泻样本中厌氧生物体（如拟杆菌、双歧杆菌、乳酸杆菌和真杆菌）的细菌计数低于恢复样本。急性肠胃炎患者正常的肠道厌氧菌群受到显著干扰。这可能导致脂肪酸含量和腹泻粪便pH值的变化。