Arnaud Martha B, Costanzo Maria C, Skrzypek Marek S, Shah Prachi, Binkley Gail, Lane Christopher, Miyasato Stuart R, Sherlock Gavin
Department of Genetics, Stanford University Medical School, Stanford, CA 94305-5120, USA.
Nucleic Acids Res. 2007 Jan;35(Database issue):D452-6. doi: 10.1093/nar/gkl899. Epub 2006 Nov 7.
The Candida Genome Database (CGD, http://www.candidagenome.org/) contains a curated collection of genomic information and community resources for researchers who are interested in the molecular biology of the opportunistic pathogen Candida albicans. With the recent release of a new assembly of the C.albicans genome, Assembly 20, C.albicans genomics has entered a new era. Although the C.albicans genome assembly continues to undergo refinement, multiple assemblies and gene nomenclatures will remain in widespread use by the research community. CGD has now taken on the responsibility of maintaining the most up-to-date version of the genome sequence by providing the data from this new assembly alongside the data from the previous assemblies, as well as any future corrections and refinements. In this database update, we describe the sequence information available for C.albicans, the sequence information contained in CGD, and the tools for sequence retrieval, analysis and comparison that CGD provides. CGD is freely accessible at http://www.candidagenome.org/ and CGD curators may be contacted by email at candida-curator@genome.stanford.edu.
念珠菌基因组数据库(CGD,http://www.candidagenome.org/)为对机会性致病原白色念珠菌分子生物学感兴趣的研究人员提供了一个经过整理的基因组信息集合和社区资源。随着白色念珠菌基因组新组装版本Assembly 20的发布,白色念珠菌基因组学进入了一个新时代。尽管白色念珠菌基因组组装仍在不断完善,但多个组装版本和基因命名法将继续被研究界广泛使用。CGD现在承担起维护最新基因组序列版本的责任,通过提供来自这个新组装版本的数据以及之前组装版本的数据,还有未来的任何修正和完善。在本次数据库更新中,我们描述了白色念珠菌可用的序列信息、CGD中包含的序列信息,以及CGD提供的序列检索、分析和比较工具。可通过http://www.candidagenome.org/免费访问CGD,可通过电子邮件candida-curator@genome.stanford.edu联系CGD管理员。