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减肥手术对青少年阻塞性睡眠呼吸暂停的影响。

Effect of bariatric surgery on obstructive sleep apnoea in adolescents.

作者信息

Kalra M, Inge T

机构信息

Division of Pulmonary Medicine, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.

出版信息

Paediatr Respir Rev. 2006 Dec;7(4):260-7. doi: 10.1016/j.prrv.2006.08.004. Epub 2006 Oct 12.

Abstract

Obese adolescents, particularly those with extreme obesity (body mass index > or =40 kg/m(2)), are developing serious medical complications at an unexpectedly high rate. As non-operative approaches to weight loss have shown less than optimal results, paediatric patients are increasingly seeking bariatric surgical intervention. Bariatric surgical procedures are designed to restrict stomach size or impair macronutrient absorption. They typically result in substantial weight loss. As with adult studies, paediatric studies generally report good obstructive sleep apnoea (OSA)-related outcomes after bariatric surgery. Therefore, in patients meeting eligibility criteria, bariatric surgery can be a valuable approach for achieving significant weight loss and resolution of serious comorbidities such as OSA. Studies that focus on long-term assessment of OSA are needed to understand whether OSA resolution after adolescent bariatric surgery is sustainable over the lifetime.

摘要

肥胖青少年,尤其是那些极度肥胖者(体重指数≥40kg/m²),正以意想不到的高比率出现严重的医学并发症。由于非手术减肥方法效果欠佳,儿科患者越来越多地寻求减肥手术干预。减肥手术旨在限制胃的大小或损害常量营养素的吸收。这些手术通常会带来显著的体重减轻。与成人研究一样,儿科研究一般报告减肥手术后阻塞性睡眠呼吸暂停(OSA)相关的良好结果。因此,对于符合资格标准的患者,减肥手术可能是实现显著体重减轻和解决诸如OSA等严重合并症的有效方法。需要开展专注于OSA长期评估的研究,以了解青少年减肥手术后OSA的缓解在一生中是否可持续。

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