Wittels E H, Thompson S
Baylor College of Medicine, Houston, Texas.
Otolaryngol Clin North Am. 1990 Aug;23(4):751-60.
OSA affects approximately 1 per cent of the adult male population and is more common among obese patients. The mechanism for the relationship between obesity and OSA may be mechanical obstruction or hypoxemia. Patients with obesity often have other medical problems that can exacerbate or complicate OSA. The physician should look for other problems such as diabetes, hypertension, and coronary disease while evaluating an obese patient with OSA. Weight loss is important either as a primary therapy or in conjunction with surgical treatment of OSA. Weight loss methods include behavior modification with diet, very low calorie diets with behavior modification, and bariatric surgery. In morbidly obese patients, more dramatic means such as bariatric surgery or very low calorie diets seem to be preferable because of the significant reduction in the length of time it takes for patients to lose weight. Because of a tendency for obese patients to regain weight, it is important to follow the patients long term to prevent the regaining of weight.
阻塞性睡眠呼吸暂停(OSA)影响约1%的成年男性人口,在肥胖患者中更为常见。肥胖与OSA之间关系的机制可能是机械性梗阻或低氧血症。肥胖患者通常还有其他可能加重OSA或使其复杂化的医疗问题。医生在评估患有OSA的肥胖患者时,应寻找其他问题,如糖尿病、高血压和冠状动脉疾病。减肥无论是作为主要治疗方法还是与OSA的手术治疗相结合都很重要。减肥方法包括饮食行为改变、结合行为改变的极低热量饮食以及减肥手术。在病态肥胖患者中,由于患者减肥所需时间显著缩短,更显著的方法如减肥手术或极低热量饮食似乎更可取。由于肥胖患者有体重反弹的倾向,长期跟踪患者以防止体重反弹很重要。