Colakoglu S, Colakoglu M, Taneli F, Cetinoz F, Turkmen M
School of Physical Education and Sports, Celal Bayar University, Manisa, Turkey.
J Sports Med Phys Fitness. 2006 Dec;46(4):570-7.
The aim of this study was to evaluate the accruing effects of conjugated linoleic acid (CLA) supplementation and aerobic exercise (Ex) on body composition and serum lipid profile in humans.
Forty-four healthy female young subjects were divided ExCLA, CLA, Ex and control (C) groups. The groups of CLA and ExCLA were supplemented with 3.6 g/d CLA whilst ExCLA and Ex groups were exercised for 30 min(-1.)3 days(-1.)week(-1) for 6 weeks.
After the study period, fat ratio, fat mass, waist and hip girths were reduced in all experimental groups and fat-free mass induced in ExCLA and CLA groups and body weight was reduced in the CLA group when compared to baseline levels. These alterations were significantly different than those of controls with the highest variations were observed in the ExCLA. There was no change in serum leptin, apo-AI, apo-B, total cholesterol, HDL, LDL, free fatty acid, and triglyceride levels. Serum glucose concentrations of ExCLA and CLA groups and insulin level of ExCLA group decreased significantly as compared to baseline levels with only serum glucose reduction of both groups were significantly different than those of controls (P<0.05). Endurance performance significantly increased in ExCLA and Ex groups (P<0.01) but did not vary in the CLA and controls.
It was shown that both CLA and exercise were effective in improvement of body composition and these effects were cumulated when they have been used together. CLA supplementation alone or with exercise seems effective on serum glucose and insulin concentrations but ineffective on endurance performance.
本研究旨在评估补充共轭亚油酸（CLA）和有氧运动（Ex）对人体身体成分和血清脂质谱的累积影响。
44名健康年轻女性受试者被分为ExCLA组、CLA组、Ex组和对照组（C）。CLA组和ExCLA组每天补充3.6克CLA，而ExCLA组和Ex组每周进行3天、每次30分钟、强度为每分钟-1的运动，持续6周。
研究期结束后，与基线水平相比，所有实验组的脂肪比例、脂肪量、腰围和臀围均降低，ExCLA组和CLA组的去脂体重增加，CLA组体重降低。这些变化与对照组有显著差异，ExCLA组变化最大。血清瘦素、载脂蛋白-AI、载脂蛋白-B、总胆固醇、高密度脂蛋白、低密度脂蛋白、游离脂肪酸和甘油三酯水平无变化。与基线水平相比，ExCLA组和CLA组的血清葡萄糖浓度以及ExCLA组的胰岛素水平显著降低，仅两组血清葡萄糖降低与对照组有显著差异（P<0.05）。ExCLA组和Ex组的耐力表现显著提高（P<0.01），但CLA组和对照组无变化。
结果表明，CLA和运动对改善身体成分均有效，两者联合使用时效果累加。单独补充CLA或与运动一起似乎对血清葡萄糖和胰岛素浓度有效，但对耐力表现无效。
