临床诊断的糖尿病神经病变：发生率、类型及严重程度。
Clinically diagnosed diabetic neuropathy: frequency, types and severity.
作者信息
Ugoya Solomon O, Echejoh Godwins O, Ugoya Tokunbo A, Agaba Emmanuel I, Puepet Fabian H, Ogunniyi Adesola
机构信息
Department of Medicine, Jos University Teaching Hospital, Jos, Nigeria.
出版信息
J Natl Med Assoc. 2006 Nov;98(11):1763-6.
OBJECTIVE
Studies of frequency of occurrence of diabetic neuropathy are few, and available studies were limited to the southern part of Nigeria. The objectives of the study were to determine the frequency of occurrence and grades of diabetes peripheral neuropathy using clinical measures.
PATIENTS AND METHODS
Consecutive patients with diabetes mellitus attending the Jos University Teaching Hospital were recruited as the study population, including 120 diabetics and 60 age-matched, nondiabetic controls. A standard proforma based on the Michigan Neuropathy Screening Instrument (MNSI) was employed to screen for diabetic neuropathy.
RESULTS
The frequency of occurrence of diabetic peripheral neuropathy was 75%. For the specific types of peripheral neuropathy, sensorimotor neuropathy was the commonest (40.4%, chi(2)=29.1; p<0.001). There was no significant difference, with severity of peripheral neuropathy among diabetics, when compared by gender. (Chi square=3.03, P value=0.081).
CONCLUSION
The frequency of occurrence of peripheral neuropathy among diabetics in Jos University Teaching Hospital from this study is rather high.
目的
糖尿病神经病变发生率的研究较少，现有研究局限于尼日利亚南部地区。本研究的目的是通过临床测量确定糖尿病周围神经病变的发生率及分级。
患者与方法
将在乔斯大学教学医院就诊的连续性糖尿病患者纳入研究人群，包括120例糖尿病患者和60例年龄匹配的非糖尿病对照者。采用基于密歇根神经病变筛查工具（MNSI）的标准表格筛查糖尿病神经病变。
结果
糖尿病周围神经病变的发生率为75%。对于特定类型的周围神经病变，感觉运动神经病变最为常见（40.4%，χ²=29.1；P<0.001）。按性别比较时，糖尿病患者周围神经病变的严重程度无显著差异（χ²=3.03，P值=0.081）。
结论
本研究中乔斯大学教学医院糖尿病患者周围神经病变的发生率相当高。
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