Vondrová H, Bartos V, Skibová J
Katedra neurologie, Institutu pro dalsí vzdĕlávání lékarů a farmaceutů, Praha.
Cas Lek Cesk. 1990 Aug 10;129(32):1004-8.
194 type I diabetics were subjected to neurological and electromyographic examinations. In 161 patients, i.e. in 83%, signs of polyneuropathy were detected, the severity of which was evaluated according to a 5-grade scale where grade 1 was the mildest and the 5th grade the most severe one. The authors proved a statistically significant correlation of the incidence and severity of polyneuropathy and the duration of diabetes. It was found that the decisive period of persistence of diabetes was 6-10 years. During this period the incidence of polyneuropathies increased from 30 to 87%. After 20 years duration of diabetes there was not only a 100% incidence of polyneuropathy, but severe affections--grade 3-5--predominated in 78%. In patients with severe grades of polyneuropathy diabetes was manifested at a significantly lower age than in patients without polyneuropathy and with a milder affection. The authors did not detect a significant relationship between the height of the patients and the incidence of polyneuropathy nor significant differences between men and women.
194名I型糖尿病患者接受了神经学和肌电图检查。在161名患者中，即83%，检测到了多发性神经病变的体征，其严重程度根据五级量表进行评估，1级为最轻微，5级为最严重。作者证明多发性神经病变的发生率和严重程度与糖尿病病程之间存在统计学上的显著相关性。发现糖尿病持续的关键时期是6至10年。在此期间，多发性神经病变的发生率从30%增加到87%。糖尿病病程达20年后，不仅多发性神经病变的发生率为100%，而且严重病变（3至5级）在78%的患者中占主导。与无多发性神经病变且病情较轻的患者相比，患有严重等级多发性神经病变的患者糖尿病发病年龄明显更低。作者未发现患者身高与多发性神经病变发生率之间存在显著关系，也未发现男性和女性之间存在显著差异。
