Molinari Michele, Watt Kymberly D S, Kruszyna Thomas, Nelson Rebecca, Walsh Mark, Huang Weei-Yuan, Nashan Bjorn, Peltekian Kevork
Queen Elizabeth II Health Sciences Center, Dalhousie University, Halifax, Nova Scotia, Canada.
Liver Transpl. 2006 Dec;12(12):1892-5. doi: 10.1002/lt.21021.
In industrialized countries, over-the-counter dietary supplements have become popular in preventing and treating an expanding list of medical conditions. Although most commercially available supplements have not been rigorously tested for safety and efficacy, they have found an enlarging market because they are considered natural. Oral supplements containing green tea extract have been marketed as effective for weight loss and to prevent and cure some solid tumors. Although there is little scientific evidence of the effectiveness of green tea extracts to improve the quality of health of regular consumers, there is an increasing body of medical literature supporting the hypothesis that they can cause serious side effects. Our experience adds to previous reports of acute liver toxicity observed in individuals consuming supplements containing green tea extract. We highlight the importance of obtaining a detailed history of dietary supplement consumption when evaluating a patient presenting with acute liver dysfunction.
在工业化国家，非处方膳食补充剂在预防和治疗越来越多的疾病方面变得很受欢迎。尽管大多数市面上可买到的补充剂尚未经过严格的安全性和有效性测试，但由于它们被认为是天然的，所以市场不断扩大。含有绿茶提取物的口服补充剂已被推销为对减肥以及预防和治疗某些实体瘤有效。虽然几乎没有科学证据表明绿茶提取物能改善普通消费者的健康状况，但越来越多的医学文献支持这样一种假设，即它们会导致严重的副作用。我们的经验补充了之前关于食用含绿茶提取物补充剂的个体出现急性肝毒性的报道。我们强调，在评估出现急性肝功能障碍的患者时，获取详细的膳食补充剂消费史的重要性。
