Lee Hyeonji, Kim Heeju, Byun Sanguine
Department of Biotechnology, Yonsei University, Seoul, 03722 Republic of Korea.
Food Sci Biotechnol. 2024 Dec 16;34(8):1661-1678. doi: 10.1007/s10068-024-01778-8. eCollection 2025 Apr.
Obesity is a public health crisis that has reached epidemic proportions worldwide, demanding urgent attention. To combat obesity, people endeavor to follow a healthy diet and regularly engage in physical activities. However, maintaining a healthy diet and physical activity is challenging, highlighting the need for novel effective therapies. This review aims to evaluate the therapeutic efficacy and safety of a well-researched functional food ingredient, green tea extract, for combating obesity. To assess the effectiveness of green tea extract, the review systematically examines various obesity indicators. It focuses on markers for body fat reduction in rodent models and humans, including weight, BMI, body fat percentage, and waist circumference. Furthermore, it explores the potential for suppressing and preventing obesity-related metabolic disorders. By thoroughly examining the effectiveness and mechanism of green tea extract, the study seeks to understand the potential of green tea extract as a nutraceutical/functional food for obesity management and prevention.
肥胖是一场已在全球达到流行程度的公共卫生危机,亟需关注。为对抗肥胖,人们努力遵循健康饮食并定期进行体育活动。然而,维持健康饮食和体育活动具有挑战性,这凸显了对新型有效疗法的需求。本综述旨在评估一种经过充分研究的功能性食品成分——绿茶提取物对抗肥胖的治疗效果和安全性。为评估绿茶提取物的有效性,该综述系统地检查了各种肥胖指标。它关注啮齿动物模型和人类中身体脂肪减少的标志物,包括体重、体重指数(BMI)、体脂百分比和腰围。此外,它还探讨了抑制和预防肥胖相关代谢紊乱的可能性。通过全面研究绿茶提取物的有效性和作用机制,该研究旨在了解绿茶提取物作为一种用于肥胖管理和预防的营养保健品/功能性食品的潜力。