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仙台病毒被模型膜的“吞噬作用”

'Phagocytosis' of sendai virus by model membranes.

作者信息

Haywood A M

出版信息

J Gen Virol. 1975 Oct;29(1):63-8. doi: 10.1099/0022-1317-29-1-63.

Abstract

Sendai viruses were attached to liposomes (vesicular model membranes) at 0 to 4 degrees C, and were then incubated at 37 degrees C. Liposomes made of phosphatidylcholine, cholesterol and gangliosides enveloped the viruses at 37 degrees C to give a picture that resembles the ingestion step of phagocytosis. Virus particles were enveloped only by liposomes that contained gangliosides which serve as Sendai virus receptors.

摘要

仙台病毒在0至4摄氏度下附着于脂质体(囊泡模型膜),然后在37摄氏度下孵育。由磷脂酰胆碱、胆固醇和神经节苷脂制成的脂质体在37摄氏度下包裹病毒,呈现出类似于吞噬作用摄取步骤的景象。病毒颗粒仅被含有作为仙台病毒受体的神经节苷脂的脂质体包裹。

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