Clackson Tim
ARIAD Pharmaceuticals Inc, Cambridge, MA 02139, USA.
Exp Biol Med (Maywood). 2006 Dec;231(11):1685-9. doi: 10.1177/153537020623101104.
Research that bridges between scientific insights and clinical application is one of the most active and exciting areas of current biomedical activity. Much of this translational work occurs through collaborations between academic and industrial institutions, taking advantage of the respective strengths and resources of the two sectors. However, such collaborations sometimes can be challenging due to differences between the cultures and priorities of the two parties. This article discusses the nature of translational research, with a focus on the academia-industry interface, analyzes the factors important for effective collaborations, and describes specific examples of successful translational research programs.
在科学见解与临床应用之间架起桥梁的研究是当前生物医学活动中最活跃、最令人兴奋的领域之一。这类转化性工作大多通过学术机构与产业机构之间的合作来开展,利用了这两个部门各自的优势和资源。然而,由于双方文化和优先事项存在差异,此类合作有时可能具有挑战性。本文讨论转化性研究的本质,重点关注学术界与产业界的接口,分析有效合作的重要因素,并描述成功的转化性研究项目的具体实例。