慢性精神分裂症中的注意网络与扣带束
Attentional networks and cingulum bundle in chronic schizophrenia.
作者信息
Nestor Paul G, Kubicki Marek, Spencer Kevin M, Niznikiewicz Margaret, McCarley Robert W, Shenton Martha E
机构信息
Department of Psychology, University of Massachusetts, Boston, MA 02125-3393, USA.
出版信息
Schizophr Res. 2007 Feb;90(1-3):308-15. doi: 10.1016/j.schres.2006.10.005. Epub 2006 Dec 5.
Abstract
Thirty patients with chronic schizophrenia and 30 age-matched controls performed the Attention Network Test (ANT). A subset of the patient group (n=18) also had available magnetic resonance diffusion tensor imaging (DTI) measures of the cingulum bundle (CB) fractional anisotropy and volume. The patients showed a significantly different pattern of ANT performance, characterized primarily by decreased alerting efficiency. In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration.
摘要
30名慢性精神分裂症患者和30名年龄匹配的对照组进行了注意力网络测试（ANT）。患者组的一个子集（n = 18）也有扣带束（CB）分数各向异性和体积的磁共振扩散张量成像（DTI）测量值。患者表现出明显不同的ANT表现模式，主要特征是警觉效率降低。此外，左侧CB分数各向异性与注意力定向显著相关。右侧CB体积较小也与警觉性降低相关，但在对药物和病程进行协变量调整后则不相关。
相似文献
1
Attentional networks and cingulum bundle in chronic schizophrenia.慢性精神分裂症中的注意网络与扣带束
Schizophr Res. 2007 Feb;90(1-3):308-15. doi: 10.1016/j.schres.2006.10.005. Epub 2006 Dec 5.
2
White matter abnormalities and brain activation in schizophrenia: a combined DTI and fMRI study.精神分裂症中的白质异常与脑激活：一项弥散张量成像（DTI）与功能磁共振成像（fMRI）的联合研究
Schizophr Res. 2007 Jan;89(1-3):1-11. doi: 10.1016/j.schres.2006.09.007. Epub 2006 Nov 7.
3
Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study.精神分裂症中扣带束完整性破坏：一项磁共振扩散张量成像研究。
Biol Psychiatry. 2003 Dec 1;54(11):1171-80. doi: 10.1016/s0006-3223(03)00419-0.
4
Anterior cingulum abnormalities in male patients with schizophrenia determined through diffusion tensor imaging.通过扩散张量成像确定的男性精神分裂症患者前扣带回异常。
Am J Psychiatry. 2004 Mar;161(3):573-5. doi: 10.1176/appi.ajp.161.3.573.
5
Diffusion tensor imaging of the superior longitudinal fasciculus and working memory in recent-onset schizophrenia.近期发病精神分裂症患者上纵束的扩散张量成像与工作记忆
Biol Psychiatry. 2008 Mar 1;63(5):512-8. doi: 10.1016/j.biopsych.2007.06.017. Epub 2007 Aug 27.
6
Impaired modulation of attention and emotion in schizophrenia.精神分裂症患者的注意和情绪调节受损。
Schizophr Bull. 2010 May;36(3):595-606. doi: 10.1093/schbul/sbn118. Epub 2008 Oct 8.
7
Anterior and posterior cingulum abnormalities and their association with psychopathology in schizophrenia: a diffusion tensor imaging study.精神分裂症中前扣带回和后扣带回异常及其与精神病理学的关联：一项扩散张量成像研究
Schizophr Res. 2007 Sep;95(1-3):215-22. doi: 10.1016/j.schres.2007.05.044. Epub 2007 Jul 30.
8
Characterizing anterior cingulate activation in chronic schizophrenia: a group and single-subject fMRI study.慢性精神分裂症患者前扣带回激活特征：一项群组及单受试者功能磁共振成像研究
Acta Psychiatr Scand. 2007 Oct;116(4):271-9. doi: 10.1111/j.1600-0447.2007.01002.x.
9
Sustained attention impairment correlates to gray matter decreases in first episode neuroleptic-naive schizophrenic patients.持续性注意力障碍与首发未使用过抗精神病药物的精神分裂症患者的灰质减少相关。
Neuroimage. 2003 Jun;19(2 Pt 1):365-75. doi: 10.1016/s1053-8119(03)00094-6.
10
Altered engagement of attention and default networks during target detection in schizophrenia.精神分裂症患者在目标检测过程中注意力和默认网络的连接改变。
Schizophr Res. 2011 Feb;125(2-3):169-73. doi: 10.1016/j.schres.2010.08.041. Epub 2010 Sep 25.
引用本文的文献
1
Abnormalities in rich-club connections are associated with an exacerbation of genetic susceptibility to schizophrenia.富集俱乐部连接异常与精神分裂症遗传易感性的加剧有关。
BMC Psychiatry. 2024 Dec 27;24(1):951. doi: 10.1186/s12888-024-06411-w.
2
White matter trajectories over the lifespan.脑白质纤维轨迹的毕生变化。
PLoS One. 2024 May 17;19(5):e0301520. doi: 10.1371/journal.pone.0301520. eCollection 2024.
3
Within-individual variability in cognitive performance in schizophrenia: A narrative review of the key literature and proposed research agenda.精神分裂症认知表现的个体内变异性：关键文献综述及拟议研究议程
Schizophr Res. 2023 Feb;252:329-334. doi: 10.1016/j.schres.2023.01.028. Epub 2023 Jan 26.
4
Gender Difference in Cognitive Function Among Stable Schizophrenia: A Network Perspective.稳定型精神分裂症认知功能的性别差异：网络视角
Neuropsychiatr Dis Treat. 2022 Dec 22;18:2991-3000. doi: 10.2147/NDT.S393586. eCollection 2022.
5
White matter tract-specific alterations in patients with primary restless legs syndrome.原发性不安腿综合征患者的白质束特异性改变。
Sci Rep. 2021 Aug 9;11(1):16116. doi: 10.1038/s41598-021-95238-6.
6
The Prediction Analysis of Autistic and Schizotypal Traits in Attentional Networks.注意网络中自闭症和分裂型特质的预测分析
Psychiatry Investig. 2021 May;18(5):417-425. doi: 10.30773/pi.2020.0251. Epub 2021 Apr 29.
7
Acute conceptual disorganization in untreated first-episode psychosis: a combined magnetic resonance spectroscopy and diffusion imaging study of the cingulum.未经治疗的首发精神病患者的急性概念组织障碍：扣带的磁共振波谱和弥散成像联合研究。
J Psychiatry Neurosci. 2021 Apr 27;46(3):E337-E346. doi: 10.1503/jpn.200167.
8
Cognitive deficits and white matter abnormalities in never-treated first-episode schizophrenia.未经治疗的首发精神分裂症患者的认知缺陷和白质异常。
Transl Psychiatry. 2020 Nov 2;10(1):368. doi: 10.1038/s41398-020-01049-0.
9
ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly.ε4 等位基因加速非痴呆老年人与年龄相关的多认知衰退和白质损伤。
Aging (Albany NY). 2020 Jun 22;12(12):12019-12031. doi: 10.18632/aging.103367.
10
The Attention Network Test Database: ADHD and Cross-Cultural Applications.注意力网络测试数据库：注意力缺陷多动障碍与跨文化应用
Front Psychol. 2020 Mar 27;11:388. doi: 10.3389/fpsyg.2020.00388. eCollection 2020.
本文引用的文献
1
Selective impairment of attentional networks of orienting and executive control in schizophrenia.精神分裂症中定向和执行控制注意网络的选择性损伤。
Schizophr Res. 2005 Oct 15;78(2-3):235-41. doi: 10.1016/j.schres.2005.01.019.
2
Modulations among the alerting, orienting and executive control networks.警觉、定向和执行控制网络之间的调节。
Exp Brain Res. 2005 Nov;167(1):27-37. doi: 10.1007/s00221-005-2365-z. Epub 2005 Oct 29.
3
The activation of attentional networks.注意网络的激活。
Neuroimage. 2005 Jun;26(2):471-9. doi: 10.1016/j.neuroimage.2005.02.004. Epub 2005 Mar 19.
4
DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity.精神分裂症中的弥散张量成像（DTI）和磁化传递率（MTR）异常：白质完整性分析
Neuroimage. 2005 Jul 15;26(4):1109-18. doi: 10.1016/j.neuroimage.2005.03.026.
5
Neuropsychological correlates of diffusion tensor imaging in schizophrenia.精神分裂症中扩散张量成像的神经心理学关联
Neuropsychology. 2004 Oct;18(4):629-637. doi: 10.1037/0894-4105.18.4.629.
6
Cingulate fasciculus integrity disruption in schizophrenia: a magnetic resonance diffusion tensor imaging study.精神分裂症中扣带束完整性破坏：一项磁共振扩散张量成像研究。
Biol Psychiatry. 2003 Dec 1;54(11):1171-80. doi: 10.1016/s0006-3223(03)00419-0.
7
Effects of irregular preparatory intervals on reaction time in schizophrenia.不规则准备间隔对精神分裂症反应时间的影响。
J Abnorm Soc Psychol. 1963 Jul;67:44-52. doi: 10.1037/h0049269.
8
Segmental set.节段性集合
Arch Gen Psychiatry. 1962 Jan;6:1-17. doi: 10.1001/archpsyc.1962.01710190003001.
9
Assessing the molecular genetics of attention networks.评估注意力网络的分子遗传学。
BMC Neurosci. 2002 Oct 4;3:14. doi: 10.1186/1471-2202-3-14.
10
Uncinate fasciculus findings in schizophrenia: a magnetic resonance diffusion tensor imaging study.精神分裂症中钩状束的研究发现：一项磁共振扩散张量成像研究
Am J Psychiatry. 2002 May;159(5):813-20. doi: 10.1176/appi.ajp.159.5.813.
Zotero 插件