Inan Omer T, Giovangrandi Laurent, Kovacs Gregory T A
Department of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.
IEEE Trans Biomed Eng. 2006 Dec;53(12 Pt 1):2507-15. doi: 10.1109/TBME.2006.880879.
Automatic electrocardiogram (ECG) beat classification is essential to timely diagnosis of dangerous heart conditions. Specifically, accurate detection of premature ventricular contractions (PVCs) is imperative to prepare for the possible onset of life-threatening arrhythmias. Although many groups have developed highly accurate algorithms for detecting PVC beats, results have generally been limited to relatively small data sets. Additionally, many of the highest classification accuracies (> 90%) have been achieved in experiments where training and testing sets overlapped significantly. Expanding the overall data set greatly reduces overall accuracy due to significant variation in ECG morphology among different patients. As a result, we believe that morphological information must be coupled with timing information, which is more constant among patients, in order to achieve high classification accuracy for larger data sets. With this approach, we combined wavelet-transformed ECG waves with timing information as our feature set for classification. We used select waveforms of 18 files of the MIT/BIH arrhythmia database, which provides an annotated collection of normal and arrhythmic beats, for training our neural-network classifier. We then tested the classifier on these 18 training files as well as 22 other files from the database. The accuracy was 95.16% over 93,281 beats from all 40 files, and 96.82% over the 22 files outside the training set in differentiating normal, PVC, and other beats.
自动心电图(ECG)搏动分类对于及时诊断危险的心脏疾病至关重要。具体而言,准确检测室性早搏(PVC)对于为可能危及生命的心律失常发作做好准备至关重要。尽管许多团队已经开发出用于检测PVC搏动的高精度算法,但结果通常仅限于相对较小的数据集。此外,许多最高的分类准确率(>90%)是在训练集和测试集有显著重叠的实验中实现的。由于不同患者之间心电图形态存在显著差异,扩大整个数据集会大大降低总体准确率。因此,我们认为形态学信息必须与患者之间更稳定的时间信息相结合,以便对更大的数据集实现高分类准确率。通过这种方法,我们将小波变换后的心电图波形与时间信息相结合,作为我们的分类特征集。我们使用了麻省理工学院/贝斯以色列女执事医疗中心(MIT/BIH)心律失常数据库中18个文件的选定波形(该数据库提供了正常和心律失常搏动的注释集合)来训练我们的神经网络分类器。然后,我们在这18个训练文件以及数据库中的其他22个文件上测试了该分类器。在所有40个文件的93281次搏动上,准确率为95.16%;在训练集之外的22个文件上,在区分正常、PVC和其他搏动方面的准确率为96.82%。