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一名双语女性的原发性进行性失语症。

Primary progressive aphasia in a bilingual woman.

作者信息

Filley Christopher M, Ramsberger Gail, Menn Lise, Wu Jiang, Reid Bessie Y, Reid Allan L

机构信息

Department of Neurology, University of Colorado School of Medicine, Denver, Colorado, USA.

出版信息

Neurocase. 2006 Oct;12(5):296-9. doi: 10.1080/13554790601126047.

DOI:10.1080/13554790601126047
PMID:17190751
Abstract

Multilingual aphasias are common because most people in the world know more than one language, but little is known of these syndromes except in patients who have had a stroke. We present a 76-year-old right-handed woman, fluent in English and Chinese, who developed anomia at age 70 and then progressed to aphasia. Functional neuroimaging disclosed mild left temporoparietal hypometabolism. Neurolinguistic testing was performed in both English and Chinese, representing a unique contribution to the literature. Results revealed conduction-like aphasia that was comparable in the two languages, although English was slightly better preserved. Primary progressive aphasia has disrupted 2 languages in a similar manner, suggesting their close neuroanatomic relationship in this case.

摘要

多语言失语症很常见,因为世界上大多数人都掌握不止一种语言,但除了中风患者外,人们对这些综合征知之甚少。我们报告一位76岁的右利手女性,她能流利使用英语和中文,70岁时出现命名性失语,随后发展为失语症。功能神经影像学显示左侧颞顶叶轻度代谢减低。我们用英语和中文进行了神经语言学测试,这对文献来说是一项独特的贡献。结果显示传导性失语症在两种语言中表现相似,尽管英语的保留情况稍好一些。原发性进行性失语症以类似方式影响了两种语言,表明在这种情况下它们的神经解剖关系密切。

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