University of Cambridge, United Kingdom.
University of Hong Kong, Hong Kong.
Am J Alzheimers Dis Other Demen. 2020 Jan-Dec;35:1533317520949708. doi: 10.1177/1533317520949708.
Speech and language impairments (aphasia) are typical of patients with Alzheimer's Disease and other dementias (ADOD) and in some pathologies are diagnostic e.g. Primary Progressive Aphasia (PPA). One question concerns the reliability and validity of symptomatology across typologically different languages. A review of aphasia in ADOD across languages suggests a similar pattern of word comprehension, naming and word finding difficulties but also evidence of language specific features in symptomatology e.g. processing of tone in Chinese languages. Given differences in linguistic impairments across languages, it is recommended that screening for aphasia in community and epidemiological studies use a Short ScreeningTest (SST) that can be delivered across dialects and languages in indigenous languages and also multilingual populations.
言语和语言障碍（失语症）是阿尔茨海默病和其他痴呆症（ADOD）患者的典型特征，在某些病理情况下具有诊断意义，例如原发性进行性失语症（PPA）。一个问题涉及到不同类型语言之间症状学的可靠性和有效性。对跨语言 ADOD 失语症的综述表明，在单词理解、命名和单词查找困难方面存在相似的模式，但也有证据表明症状学具有语言特异性特征，例如在汉语中处理语调。鉴于不同语言之间的语言障碍存在差异，建议在社区和流行病学研究中使用短筛查测试（SST）来筛查失语症，该测试可以在不同方言和语言中使用，也可以在土著语言和多语言人群中使用。
