Jongenelis K, Gerritsen D L, Pot A M, Beekman A T F, Eisses A M H, Kluiter H, Ribbe M W
VU Medical Center/Institute for Research in Extramural Medicine, Department of Nursing Home Medicine, Amsterdam, The Netherlands.
Int J Geriatr Psychiatry. 2007 Sep;22(9):837-42. doi: 10.1002/gps.1748.
To construct a patient- and user-friendly shortened version of the Geriatric Depression Scale (GDS) that is especially suitable for nursing home patients.
The study was carried out on two different data bases including 23 Dutch nursing homes. Data on the GDS (n = 410), the Mini Mental State Examination (n = 410) and a diagnostic interview (SCAN; n = 333), were collected by trained clinicians. Firstly, the items of the GDS-15 were judged on their clinical applicability by three clinical experts. Subsequently, items that were identified as unsuitable were removed using the data of the Assess project (n = 77), and internal consistency was calculated. Secondly, with respect to criterion validity (sensitivity, specitivity, area under ROC and positive and negative predictive values), the newly constructed shortened GDS was validated in the AGED data set (n = 333), using DSM-IV diagnosis for depression as measured by the SCAN as 'gold standard'.
The eight-item GDS that resulted from stage 1 showed good internal consistency in both the Assess data set (alpha = 0.86) and the AGED dataset (alpha = 0.80). In the AGED dataset, high sensitivity rates of 96.3% for major depression and 83.0% for minor depression were found, with a specificity rate of 71.7% at a cut-off point of 2/3.
The GDS-8 has good psychometric properties. Given that the GDS-8 is less burdening for the patient, more comfortable to use and less time consuming, it may be a more feasible screening test for the frail nursing home population.
构建一个对患者和使用者友好的老年抑郁量表（GDS）简化版，特别适用于养老院患者。
该研究在两个不同的数据库上进行，包括23家荷兰养老院。由经过培训的临床医生收集GDS（n = 410）、简易精神状态检查表（n = 410）和诊断访谈（SCAN；n = 333）的数据。首先，由三位临床专家对GDS - 15的条目进行临床适用性判断。随后，使用评估项目的数据（n = 77）去除被认定不合适的条目，并计算内部一致性。其次，关于效标效度（敏感性、特异性、ROC曲线下面积以及阳性和阴性预测值），以SCAN测量的DSM - IV抑郁症诊断为“金标准”，在老年数据集（n = 333）中对新构建的简化GDS进行验证。
第一阶段得出的八项GDS在评估数据集（α = 0.86）和老年数据集中（α = 0.80）均显示出良好的内部一致性。在老年数据集中，重度抑郁症的高敏率为96.3%，轻度抑郁症为83.0%，在临界值为2/3时特异性率为71.7%。
GDS - 8具有良好的心理测量特性。鉴于GDS - 8对患者负担较小、使用更舒适且耗时更少，它可能是针对体弱养老院人群更可行的筛查测试。
