Weiden Peter J, Young Allan H, Buckley Peter F
Department of Psychiatry, Schizophrenia Research Program, State University of New York Downstate Medical Center, Brooklyn, USA.
J Clin Psychiatry. 2006 Nov;67(11):e15. doi: 10.4088/jcp.1106e15.
In the presentation "Prevalence of and Factors Influencing the Switching of Antipsychotic Medications," Weiden defines the recovery approach for the treatment of schizophrenia, focuses on reasons for switching antipsychotic medications, and offers recommendations for evaluating switch studies. In "Combining and Switching Medications in Bipolar Disorder," Young discusses the similarities and differences between schizophrenia and bipolar disorder, offers recommendations for switching medications in bipolar disorder, and evaluates studies of atypical antipsychotics in the treatment of bipolar disorder. Buckley's presentation, "Differential Pharmacology of Atypical Antipsychotics: Clinical Implications," examines response rates in patients with schizophrenia after switching antipsychotic medications, outlines receptor-binding profiles of atypical antipsychotics, highlights adverse events that may occur when switching antipsychotic medications, and offers recommendations for treating those adverse events.
在题为“抗精神病药物换药的患病率及影响因素”的报告中，魏登定义了精神分裂症的康复治疗方法，重点阐述了抗精神病药物换药的原因，并为评估换药研究提供了建议。在“双相情感障碍的联合用药与换药”中，杨探讨了精神分裂症和双相情感障碍之间的异同，为双相情感障碍的换药提供了建议，并评估了非典型抗精神病药物治疗双相情感障碍的研究。巴克利的报告“非典型抗精神病药物的差异药理学：临床意义”研究了抗精神病药物换药后精神分裂症患者的反应率，概述了非典型抗精神病药物的受体结合情况，强调了抗精神病药物换药时可能发生的不良事件，并为治疗这些不良事件提供了建议。
