Siéroff Eric, Decaix Caroline, Chokron Sylvie, Bartolomeo Paolo
Universite Rene Descartes (Paris 5), Laboratoire de Psychologie et Neurosciences Cognitives (CNRS FRE 2987), Boulogne-Billancourt, France.
Neuropsychology. 2007 Jan;21(1):94-113. doi: 10.1037/0894-4105.21.1.94.
Twenty-six patients suffering from damage to the right side of the brain, 19 of whom exhibited signs of left neglect, as well as 32 matched controls, ran 3 spatial cuing tasks. Patients were also tested with 2 cancellation tests, a line-bisection test, the copy of a complex drawing, and a visual extinction procedure. Results first showed correlations between extinction and cancellation tests performance on one hand, and between line bisection and copy on the other hand. Second, results demonstrated that an engagement deficit toward contralesional targets appeared to be the most striking feature of neglect, and the engagement score was correlated with the cancellation score and extinction. Most patients with neglect also presented a deficit in disengagement, a deficit of inhibition of return, and probably a deficit of alertness. Deficits in engagement and in disengagement, as well as poor scores in cancellation tests, seemed to be related with posterior cortical and subcortical lesions. Most important, even if an endogenous deficit (frequently related with a thalamic lesion) could aggravate the neglect behavior, neglect syndrome was mainly explained by a deficit of exogenous attention.
26名右脑受损患者（其中19名表现出左侧忽视症状）以及32名匹配的对照组人员进行了3项空间线索任务测试。患者还接受了2项划消测试、一项直线二等分测试、临摹一幅复杂图形以及一项视觉消失测试。结果首先显示，一方面消失测试与划消测试的表现之间存在相关性，另一方面直线二等分测试与临摹之间存在相关性。其次，结果表明，对患侧对侧目标的参与缺陷似乎是忽视最显著的特征，且参与分数与划消分数及消失测试相关。大多数忽视患者还存在脱离缺陷、返回抑制缺陷，可能还有警觉缺陷。参与和脱离缺陷，以及划消测试中的低分，似乎与后皮质和皮质下病变有关。最重要的是，即使内源性缺陷（通常与丘脑病变有关）会加重忽视行为，但忽视综合征主要是由外源性注意力缺陷所导致的。
