Lawrence Valerie A, Hilsenbeck Susan G, Noveck Helaine, Poses Roy M, Carson Jeffrey L
Division of General Medicine, Audie L. Murphy Division, South Texas Veterans Health Care System, San Antonio, TX, USA.
Arch Intern Med. 2002 Oct 14;162(18):2053-7. doi: 10.1001/archinte.162.18.2053.
Most evidence guiding perioperative medical risk management of patients undergoing hip fracture repair focuses on cardiac and thromboembolic risk. Little is known of the relative clinical importance of other complications.
To systematically map incidence and outcomes of a broad spectrum of medical complications after hip fracture repair.
Retrospective cohort study of patients 60 years or older in 20 academic, community, and Veterans Affairs hospitals. Data on complications and mortality were abstracted from medical records by trained abstractors using standardized, pretested forms or the National Death Index.
Of 8930 patients, 1737 (19%) had postoperative medical complications. Cardiac and pulmonary complications were most frequent (8% and 4% of patients, respectively). Similar numbers of patients had serious cardiac or pulmonary complications (2% and 3%, respectively). Other complications were gastrointestinal tract bleeding (2%), combined cardiopulmonary complications (1%), venous thromboembolism (1%), and transient ischemic attack or stroke (1%). Renal failure and septic shock were rare. After the index complication, 416 patients had 587 additional complications. Mortality was similar for serious cardiac or pulmonary complications (30 day: 22% and 17%, respectively; 1 year: 36% and 44%, respectively) and highest for patients with multiple complications (30 day: 29%-38%; 1 year: 43%-62%). Complications and death occurred significantly earlier for serious cardiac than for serious pulmonary complications (1 vs 4 days, 2 vs 8 days, P<.001); length of stay for patients surviving these complications was similar.
Most patients had no medical complications after hip fracture repair. Serious cardiac and pulmonary complications were equally important in frequency, mortality, and survivors' length of stay. Patients with multiple complications had especially poor prognosis.
大多数指导髋部骨折修复患者围手术期医疗风险管理的证据都集中在心脏和血栓栓塞风险上。对于其他并发症的相对临床重要性知之甚少。
系统梳理髋部骨折修复后广泛的医疗并发症的发生率和结局。
对20家学术、社区和退伍军人事务医院中60岁及以上的患者进行回顾性队列研究。并发症和死亡率数据由经过培训的提取人员使用标准化的、经过预测试的表格或国家死亡索引从医疗记录中提取。
8930例患者中,1737例(19%)有术后医疗并发症。心脏和肺部并发症最为常见(分别占患者的8%和4%)。发生严重心脏或肺部并发症的患者数量相似(分别为2%和3%)。其他并发症包括胃肠道出血(2%)、心肺联合并发症(1%)、静脉血栓栓塞(1%)以及短暂性脑缺血发作或中风(1%)。肾衰竭和感染性休克很少见。在首次出现并发症后,416例患者又出现了587例额外并发症。严重心脏或肺部并发症的死亡率相似(30天:分别为22%和17%;1年:分别为36%和44%),而有多种并发症的患者死亡率最高(30天:29%-38%;1年:43%-62%)。严重心脏并发症比严重肺部并发症的并发症和死亡发生时间明显更早(分别为1天对4天,2天对8天,P<0.001);这些并发症存活患者的住院时间相似。
大多数患者在髋部骨折修复后没有医疗并发症。严重心脏和肺部并发症在发生率、死亡率和幸存者住院时间方面同样重要。有多种并发症的患者预后尤其差。