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酒精性胰腺炎中的胰腺肿大:患病率及自然病史。

Pancreatic enlargement in alcoholic pancreatitis: prevalence and natural history.

作者信息

Friedman A D, Dutta S K, Dubin E H, Medhat A, Keramati B, Whitley N

机构信息

Department of Medicine, Veterans Administration Medical Center, University of Maryland School of Medicine, Baltimore.

出版信息

J Clin Gastroenterol. 1991 Dec;13(6):666-72. doi: 10.1097/00004836-199112000-00011.

Abstract

We determined the prevalence and natural history of pancreatic enlargement by abdominal ultrasonography or computed tomography in 72 patients with alcoholic pancreatitis. Pancreatic enlargement was observed in 54 patients (75%); it was diffuse in 28 (52%) and focal in 26 (48%). The focal enlargement was frequently cystic (50%), while the diffuse enlargement was only occasionally cystic (7%). Sequential imaging of the pancreas in 29 patients demonstrated partial to total resolution of pancreatic enlargement in greater than 50% during 6 months of follow-up. Determination of serum amylase and p-isoamylase activity was neither sensitive nor specific for pancreatic enlargement in alcoholic pancreatitis.

摘要

我们通过腹部超声或计算机断层扫描确定了72例酒精性胰腺炎患者胰腺肿大的患病率和自然病程。54例患者(75%)观察到胰腺肿大;其中28例(52%)为弥漫性肿大,26例(48%)为局灶性肿大。局灶性肿大常为囊性(50%),而弥漫性肿大仅偶尔为囊性(7%)。对29例患者的胰腺进行连续成像显示,在6个月的随访期间,超过50%的患者胰腺肿大部分至完全消退。测定血清淀粉酶和对异淀粉酶活性对酒精性胰腺炎患者的胰腺肿大既不敏感也无特异性。

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